Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS43000120MCVENSG00000171552.14protein_codingBCL2L1NoNo598A0A0S2Z3C5
Q07817
Q5TE63
TCGA Plot Options
Drug Information
GeneBCL2L1
DrugBank IDDB13044
Drug NameGossypol
Target IDBE0003510
UniProt IDQ07817
Regulation Type
PubMed IDs16020667
CitationsBauer JA, Trask DK, Kumar B, Los G, Castro J, Lee JS, Chen J, Wang S, Bradford CR, Carey TE: Reversal of cisplatin resistance with a BH3 mimetic, (-)-gossypol, in head and neck cancer cells: role of wild-type p53 and Bcl-xL. Mol Cancer Ther. 2005 Jul;4(7):1096-104.
GroupsInvestigational
Direct ClassificationSesquiterpenoids
SMILESCC(C)C1=C2C=C(C)C(=C(O)C2=C(C=O)C(O)=C1O)C1=C(O)C2=C(C=O)C(O)=C(O)C(C(C)C)=C2C=C1C
Pathways
PharmGKB
ChEMBLCHEMBL51483