| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30001246 | HIV | ENSG00000198851.10 | protein_coding | CD3E | No | No | 916 | P07766 |
| TVIS30001964 | HIV | ENSG00000198851.10 | protein_coding | CD3E | No | No | 916 | P07766 |
| TVIS30011637 | HIV | ENSG00000198851.10 | protein_coding | CD3E | No | No | 916 | P07766 |
| TVIS30031388 | HIV | ENSG00000198851.10 | protein_coding | CD3E | No | No | 916 | P07766 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | CD3E |
|---|---|
| DrugBank ID | DB06606 |
| Drug Name | Teplizumab |
| Target ID | BE0000274 |
| UniProt ID | P07766 |
| Regulation Type | antibody |
| PubMed IDs | 10716879; 31523950 |
| Citations | Xu D, Alegre ML, Varga SS, Rothermel AL, Collins AM, Pulito VL, Hanna LS, Dolan KP, Parren PW, Bluestone JA, Jolliffe LK, Zivin RA: In vitro characterization of five humanized OKT3 effector function variant antibodies. Cell Immunol. 2000 Feb 25;200(1):16-26. doi: 10.1006/cimm.2000.1617.@@Gaglia J, Kissler S: Anti-CD3 Antibody for the Prevention of Type 1 Diabetes: A Story of Perseverance. Biochemistry. 2019 Oct 8;58(40):4107-4111. doi: 10.1021/acs.biochem.9b00707. Epub 2019 Sep 24. |
| Groups | Approved; Investigational |
| Direct Classification | Peptides |
| SMILES | |
| Pathways | |
| PharmGKB | |
| ChEMBL |
