| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10019549 | HBV | ENSG00000182578.14 | protein_coding | CSF1R | No | No | 1436 | P07333 |
| TVIS10036143 | HBV | ENSG00000182578.14 | protein_coding | CSF1R | No | No | 1436 | P07333 |
| TVIS10062766 | HBV | ENSG00000182578.14 | protein_coding | CSF1R | No | No | 1436 | P07333 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CSF1R |
|---|---|
| DrugBank ID | DB01268 |
| Drug Name | Sunitinib |
| Target ID | BE0000853 |
| UniProt ID | P07333 |
| Regulation Type | inhibitor |
| PubMed IDs | 16648572; 17367763 |
| Citations | Guo J, Marcotte PA, McCall JO, Dai Y, Pease LJ, Michaelides MR, Davidsen SK, Glaser KB: Inhibition of phosphorylation of the colony-stimulating factor-1 receptor (c-Fms) tyrosine kinase in transfected cells by ABT-869 and other tyrosine kinase inhibitors. Mol Cancer Ther. 2006 Apr;5(4):1007-13.@@Roskoski R Jr: Sunitinib: a VEGF and PDGF receptor protein kinase and angiogenesis inhibitor. Biochem Biophys Res Commun. 2007 May 4;356(2):323-8. Epub 2007 Mar 7. |
| Groups | Approved; Investigational |
| Direct Classification | Indolines |
| SMILES | CCN(CC)CCNC(=O)C1=C(C)NC(C=C2/C(=O)NC3=C2C=C(F)C=C3)=C1C |
| Pathways | |
| PharmGKB | PA162372840 |
| ChEMBL | CHEMBL535 |
