| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20003375 | HPV | ENSG00000204681.11 | protein_coding | GABBR1 | No | No | 2550 | Q5SUJ9 Q8IW08 Q9UBS5 |
| TVIS20006860 | HPV | ENSG00000204681.11 | protein_coding | GABBR1 | No | No | 2550 | Q5SUJ9 Q8IW08 Q9UBS5 |
| TVIS44022560 | HTLV-1 | ENSG00000204681.11 | protein_coding | GABBR1 | No | No | 2550 | Q5SUJ9 Q8IW08 Q9UBS5 |
| TVIS44022561 | HTLV-1 | ENSG00000204681.11 | protein_coding | GABBR1 | No | No | 2550 | Q5SUJ9 Q8IW08 Q9UBS5 |
| TVIS44050516 | HTLV-1 | ENSG00000204681.11 | protein_coding | GABBR1 | No | No | 2550 | Q5SUJ9 Q8IW08 Q9UBS5 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | GABBR1 |
|---|---|
| DrugBank ID | DB00363 |
| Drug Name | Clozapine |
| Target ID | BE0000217 |
| UniProt ID | Q9UBS5 |
| Regulation Type | positive modulator |
| PubMed IDs | 32203158 |
| Citations | Nair PC, McKinnon RA, Miners JO, Bastiampillai T: Binding of clozapine to the GABA(B) receptor: clinical and structural insights. Mol Psychiatry. 2020 Sep;25(9):1910-1919. doi: 10.1038/s41380-020-0709-5. Epub 2020 Mar 13. |
| Groups | Approved |
| Direct Classification | Dibenzodiazepines |
| SMILES | CN1CCN(CC1)C1=NC2=CC(Cl)=CC=C2NC2=CC=CC=C12 |
| Pathways | |
| PharmGKB | PA449061 |
| ChEMBL | CHEMBL42 |
