| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10059660 | HBV | ENSG00000130005.13 | protein_coding | GAMT | No | No | 2593 | Q14353 |
| TVIS10059193 | HBV | ENSG00000130005.13 | protein_coding | GAMT | No | No | 2593 | Q14353 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | GAMT |
|---|---|
| DrugBank ID | DB00536 |
| Drug Name | Guanidine |
| Target ID | BE0000567 |
| UniProt ID | Q14353 |
| Regulation Type | |
| PubMed IDs | 17139284; 17016423; 15533043; 179611; 10592235 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Komoto J, Yamada T, Takata Y, Konishi K, Ogawa H, Gomi T, Fujioka M, Takusagawa F: Catalytic mechanism of guanidinoacetate methyltransferase: crystal structures of guanidinoacetate methyltransferase ternary complexes. Biochemistry. 2004 Nov 16;43(45):14385-94.@@Karelin AA, Mardashev SR: [The stimulating effect of cyclic AMP, glucagon and insulin on guanidine acetate-N-methyltransferase activity in rat liver and pancreas]. Biokhimiia. 1976 Feb;41(2):316-23.@@Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. |
| Groups | Approved |
| Direct Classification | Guanidines |
| SMILES | NC(N)=N |
| Pathways | |
| PharmGKB | PA164781028 |
| ChEMBL | CHEMBL821 |
