Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10020921HBVENSG00000101958.14protein_codingGLRA2NoNo2742P23416
TVIS10020920HBVENSG00000101958.14protein_codingGLRA2NoNo2742P23416
TVIS10014897HBVENSG00000101958.14protein_codingGLRA2NoNo2742P23416
TVIS10014898HBVENSG00000101958.14protein_codingGLRA2NoNo2742P23416
TVIS10020940HBVENSG00000101958.14protein_codingGLRA2NoNo2742P23416
TVIS10031645HBVENSG00000101958.14protein_codingGLRA2NoNo2742P23416
TVIS10031646HBVENSG00000101958.14protein_codingGLRA2NoNo2742P23416
TVIS10033377HBVENSG00000101958.14protein_codingGLRA2NoNo2742P23416
TVIS10042368HBVENSG00000101958.14protein_codingGLRA2NoNo2742P23416
TVIS30072819HIVENSG00000101958.14protein_codingGLRA2NoNo2742P23416
TCGA Plot Options
Drug Information
GeneGLRA2
DrugBank IDDB00431
Drug NameLindane
Target IDBE0000745
UniProt IDP23416
Regulation Typeantagonist
PubMed IDs12614680; 20600211
CitationsVale C, Fonfria E, Bujons J, Messeguer A, Rodriguez-Farre E, Sunol C: The organochlorine pesticides gamma-hexachlorocyclohexane (lindane), alpha-endosulfan and dieldrin differentially interact with GABA(A) and glycine-gated chloride channels in primary cultures of cerebellar granule cells. Neuroscience. 2003;117(2):397-403.@@Heusinkveld HJ, Thomas GO, Lamot I, van den Berg M, Kroese AB, Westerink RH: Dual actions of lindane (gamma-hexachlorocyclohexane) on calcium homeostasis and exocytosis in rat PC12 cells. Toxicol Appl Pharmacol. 2010 Oct 1;248(1):12-9. doi: 10.1016/j.taap.2010.06.013. Epub 2010 Jun 21.
GroupsApproved; Withdrawn
Direct ClassificationCyclohexyl halides
SMILESCl[C@H]1[C@H](Cl)[C@@H](Cl)[C@@H](Cl)[C@H](Cl)[C@H]1Cl
Pathways
PharmGKBPA164754914
ChEMBLCHEMBL15891