Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS20020663HPVENSG00000178623.13protein_codingGPR35NoNo2859Q9HC97
TVIS44024776HTLV-1ENSG00000178623.13protein_codingGPR35NoNo2859Q9HC97
TVIS44024777HTLV-1ENSG00000178623.13protein_codingGPR35NoNo2859Q9HC97
TCGA Plot Options
Drug Information
GeneGPR35
DrugBank IDDB11156
Drug NamePyrantel
Target IDBE0005562
UniProt IDQ9HC97
Regulation Type
PubMed IDs20826425
CitationsZhao P, Sharir H, Kapur A, Cowan A, Geller EB, Adler MW, Seltzman HH, Reggio PH, Heynen-Genel S, Sauer M, Chung TD, Bai Y, Chen W, Caron MG, Barak LS, Abood ME: Targeting of the orphan receptor GPR35 by pamoic acid: a potent activator of extracellular signal-regulated kinase and beta-arrestin2 with antinociceptive activity. Mol Pharmacol. 2010 Oct;78(4):560-8. doi: 10.1124/mol.110.066746. Epub 2010 Jul 22.
GroupsApproved; Vet_approved
Direct ClassificationHydropyrimidines
SMILES[H]C(=C([H])C1=NCCCN1C)C1=CC=CS1
Pathways
PharmGKB
ChEMBLCHEMBL1626223