| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20020663 | HPV | ENSG00000178623.13 | protein_coding | GPR35 | No | No | 2859 | Q9HC97 |
| TVIS44024776 | HTLV-1 | ENSG00000178623.13 | protein_coding | GPR35 | No | No | 2859 | Q9HC97 |
| TVIS44024777 | HTLV-1 | ENSG00000178623.13 | protein_coding | GPR35 | No | No | 2859 | Q9HC97 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | GPR35 |
|---|---|
| DrugBank ID | DB00695 |
| Drug Name | Furosemide |
| Target ID | BE0005562 |
| UniProt ID | Q9HC97 |
| Regulation Type | agonist |
| PubMed IDs | 22236570; 29860395; 25805994 |
| Citations | Yang Y, Fu A, Wu X, Reagan JD: GPR35 is a target of the loop diuretic drugs bumetanide and furosemide. Pharmacology. 2012;89(1-2):13-7. doi: 10.1159/000335127. Epub 2012 Jan 10.@@Divorty N, Milligan G, Graham D, Nicklin SA: The Orphan Receptor GPR35 Contributes to Angiotensin II-Induced Hypertension and Cardiac Dysfunction in Mice. Am J Hypertens. 2018 Aug 3;31(9):1049-1058. doi: 10.1093/ajh/hpy073.@@Divorty N, Mackenzie AE, Nicklin SA, Milligan G: G protein-coupled receptor 35: an emerging target in inflammatory and cardiovascular disease. Front Pharmacol. 2015 Mar 10;6:41. doi: 10.3389/fphar.2015.00041. eCollection 2015. |
| Groups | Approved; Vet_approved |
| Direct Classification | Aminobenzenesulfonamides |
| SMILES | NS(=O)(=O)C1=C(Cl)C=C(NCC2=CC=CO2)C(=C1)C(O)=O |
| Pathways | Furosemide Action Pathway |
| PharmGKB | PA449719 |
| ChEMBL | CHEMBL35 |
