| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20052617 | HPV | ENSG00000086696.11 | protein_coding | HSD17B2 | No | Yes | 3294 | P37059 |
| TVIS20052815 | HPV | ENSG00000086696.11 | protein_coding | HSD17B2 | No | Yes | 3294 | P37059 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | HSD17B2 |
|---|---|
| DrugBank ID | DB13952 |
| Drug Name | Estradiol acetate |
| Target ID | BE0000006 |
| UniProt ID | P37059 |
| Regulation Type | |
| PubMed IDs | 21972996 |
| Citations | Wetzel M, Marchais-Oberwinkler S, Perspicace E, Moller G, Adamski J, Hartmann RW: Introduction of an electron withdrawing group on the hydroxyphenylnaphthol scaffold improves the potency of 17beta-hydroxysteroid dehydrogenase type 2 (17beta-HSD2) inhibitors. J Med Chem. 2011 Nov 10;54(21):7547-57. doi: 10.1021/jm2008453. Epub 2011 Oct 19. |
| Groups | Approved; Investigational; Vet_approved |
| Direct Classification | Steroid esters |
| SMILES | [H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@]1([H])C3=CC=C(OC(C)=O)C=C3CC[C@@]21[H] |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL1200430 |
