Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS20052617HPVENSG00000086696.11protein_codingHSD17B2NoYes3294P37059
TVIS20052815HPVENSG00000086696.11protein_codingHSD17B2NoYes3294P37059
TCGA Plot Options
Drug Information
GeneHSD17B2
DrugBank IDDB13955
Drug NameEstradiol dienanthate
Target IDBE0000006
UniProt IDP37059
Regulation Type
PubMed IDs21972996
CitationsWetzel M, Marchais-Oberwinkler S, Perspicace E, Moller G, Adamski J, Hartmann RW: Introduction of an electron withdrawing group on the hydroxyphenylnaphthol scaffold improves the potency of 17beta-hydroxysteroid dehydrogenase type 2 (17beta-HSD2) inhibitors. J Med Chem. 2011 Nov 10;54(21):7547-57. doi: 10.1021/jm2008453. Epub 2011 Oct 19.
GroupsApproved; Investigational; Vet_approved
Direct ClassificationSteroid esters
SMILESCCCCCCC(=O)O[C@H]1CC[C@H]2[C@@H]3CCC4=CC(OC(=O)CCCCCC)=CC=C4[C@H]3CC[C@]12C
Pathways
PharmGKB
ChEMBL