| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10060311 | HBV | ENSG00000171105.14 | protein_coding | INSR | Yes | No | 3643 | P06213 |
| TVIS30087023 | HIV | ENSG00000171105.14 | protein_coding | INSR | Yes | No | 3643 | P06213 |
| TVIS30074133 | HIV | ENSG00000171105.14 | protein_coding | INSR | Yes | No | 3643 | P06213 |
| TVIS20007384 | HPV | ENSG00000171105.14 | protein_coding | INSR | Yes | No | 3643 | P06213 |
| TVIS20007385 | HPV | ENSG00000171105.14 | protein_coding | INSR | Yes | No | 3643 | P06213 |
| TVIS20004195 | HPV | ENSG00000171105.14 | protein_coding | INSR | Yes | No | 3643 | P06213 |
| TVIS20065658 | HPV | ENSG00000171105.14 | protein_coding | INSR | Yes | No | 3643 | P06213 |
| TVIS20043075 | HPV | ENSG00000171105.14 | protein_coding | INSR | Yes | No | 3643 | P06213 |
| TVIS20024956 | HPV | ENSG00000171105.14 | protein_coding | INSR | Yes | No | 3643 | P06213 |
| TVIS20034877 | HPV | ENSG00000171105.14 | protein_coding | INSR | Yes | No | 3643 | P06213 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | INSR |
|---|---|
| DrugBank ID | DB00046 |
| Drug Name | Insulin lispro |
| Target ID | BE0000033 |
| UniProt ID | P06213 |
| Regulation Type | agonist |
| PubMed IDs | 11752352; 8964871; 8937933; 20424816; 27512793 |
| Citations | Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5.@@Jehle PM, Fussgaenger RD, Kunze U, Dolderer M, Warchol W, Koop I: The human insulin analog insulin lispro improves insulin binding on circulating monocytes of intensively treated insulin-dependent diabetes mellitus patients. J Clin Endocrinol Metab. 1996 Jun;81(6):2319-27.@@Jehle PM, Fussganger RD, Seibold A, Luttke B, Bohm BO: Pharmacodynamics of insulin Lispro in 2 patients with type II diabetes mellitus. Int J Clin Pharmacol Ther. 1996 Nov;34(11):498-503.@@Sciacca L, Cassarino MF, Genua M, Pandini G, Le Moli R, Squatrito S, Vigneri R: Insulin analogues differently activate insulin receptor isoforms and post-receptor signalling. Diabetologia. 2010 Aug;53(8):1743-53. doi: 10.1007/s00125-010-1760-6. Epub 2010 Apr 28.@@De Meyts P: The Insulin Receptor and Its Signal Transduction Network . |
| Groups | Approved |
| Direct Classification | Peptides |
| SMILES | |
| Pathways | |
| PharmGKB | PA164747059 |
| ChEMBL | CHEMBL1201538 |
