| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10036457 | HBV | ENSG00000182541.18 | protein_coding | LIMK2 | No | No | 3985 | P53671 |
| TVIS30012966 | HIV | ENSG00000182541.18 | protein_coding | LIMK2 | No | No | 3985 | P53671 |
| TVIS30017255 | HIV | ENSG00000182541.18 | protein_coding | LIMK2 | No | No | 3985 | P53671 |
| TVIS30017349 | HIV | ENSG00000182541.18 | protein_coding | LIMK2 | No | No | 3985 | P53671 |
| TVIS30055384 | HIV | ENSG00000182541.18 | protein_coding | LIMK2 | No | No | 3985 | P53671 |
| TVIS30055385 | HIV | ENSG00000182541.18 | protein_coding | LIMK2 | No | No | 3985 | P53671 |
| TVIS30055386 | HIV | ENSG00000182541.18 | protein_coding | LIMK2 | No | No | 3985 | P53671 |
| TVIS30055387 | HIV | ENSG00000182541.18 | protein_coding | LIMK2 | No | No | 3985 | P53671 |
| TVIS30055388 | HIV | ENSG00000182541.18 | protein_coding | LIMK2 | No | No | 3985 | P53671 |
| TVIS30055389 | HIV | ENSG00000182541.18 | protein_coding | LIMK2 | No | No | 3985 | P53671 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | LIMK2 |
|---|---|
| DrugBank ID | DB12010 |
| Drug Name | Fostamatinib |
| Target ID | BE0009456 |
| UniProt ID | P53671 |
| Regulation Type | inhibitor |
| PubMed IDs | 26516587 |
| Citations | Rolf MG, Curwen JO, Veldman-Jones M, Eberlein C, Wang J, Harmer A, Hellawell CJ, Braddock M: In vitro pharmacological profiling of R406 identifies molecular targets underlying the clinical effects of fostamatinib. Pharmacol Res Perspect. 2015 Oct;3(5):e00175. doi: 10.1002/prp2.175. Epub 2015 Sep 4. |
| Groups | Approved; Investigational |
| Direct Classification | Methoxyanilines |
| SMILES | COC1=CC(NC2=NC=C(F)C(NC3=NC4=C(OC(C)(C)C(=O)N4COP(O)(O)=O)C=C3)=N2)=CC(OC)=C1OC |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL2103830 |
