Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10012683HBVENSG00000006432.16protein_codingMAP3K9NoNo4293G3V347
J3KPI6
P80192
TVIS20014497HPVENSG00000006432.16protein_codingMAP3K9NoNo4293G3V347
J3KPI6
P80192
TVIS20014504HPVENSG00000006432.16protein_codingMAP3K9NoNo4293G3V347
J3KPI6
P80192
TVIS20014515HPVENSG00000006432.16protein_codingMAP3K9NoNo4293G3V347
J3KPI6
P80192
TVIS20014496HPVENSG00000006432.16protein_codingMAP3K9NoNo4293G3V347
J3KPI6
P80192
TVIS20014518HPVENSG00000006432.16protein_codingMAP3K9NoNo4293G3V347
J3KPI6
P80192
TVIS20014519HPVENSG00000006432.16protein_codingMAP3K9NoNo4293G3V347
J3KPI6
P80192
TVIS20014505HPVENSG00000006432.16protein_codingMAP3K9NoNo4293G3V347
J3KPI6
P80192
TVIS20014520HPVENSG00000006432.16protein_codingMAP3K9NoNo4293G3V347
J3KPI6
P80192
TVIS20014506HPVENSG00000006432.16protein_codingMAP3K9NoNo4293G3V347
J3KPI6
P80192
TCGA Plot Options
Drug Information
GeneMAP3K9
DrugBank IDDB12010
Drug NameFostamatinib
Target IDBE0004386
UniProt IDP80192
Regulation Typeinhibitor
PubMed IDs26516587
CitationsRolf MG, Curwen JO, Veldman-Jones M, Eberlein C, Wang J, Harmer A, Hellawell CJ, Braddock M: In vitro pharmacological profiling of R406 identifies molecular targets underlying the clinical effects of fostamatinib. Pharmacol Res Perspect. 2015 Oct;3(5):e00175. doi: 10.1002/prp2.175. Epub 2015 Sep 4.
GroupsApproved; Investigational
Direct ClassificationMethoxyanilines
SMILESCOC1=CC(NC2=NC=C(F)C(NC3=NC4=C(OC(C)(C)C(=O)N4COP(O)(O)=O)C=C3)=N2)=CC(OC)=C1OC
Pathways
PharmGKB
ChEMBLCHEMBL2103830