| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10041084 | HBV | ENSG00000111142.14 | protein_coding | METAP2 | No | No | 10988 | A0A140VJE3 F8VQZ7 P50579 |
| TVIS30033822 | HIV | ENSG00000111142.14 | protein_coding | METAP2 | No | No | 10988 | A0A140VJE3 F8VQZ7 P50579 |
| TVIS20050655 | HPV | ENSG00000111142.14 | protein_coding | METAP2 | No | No | 10988 | A0A140VJE3 F8VQZ7 P50579 |
| TVIS20050272 | HPV | ENSG00000111142.14 | protein_coding | METAP2 | No | No | 10988 | A0A140VJE3 F8VQZ7 P50579 |
| TVIS20050296 | HPV | ENSG00000111142.14 | protein_coding | METAP2 | No | No | 10988 | A0A140VJE3 F8VQZ7 P50579 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | METAP2 |
|---|---|
| DrugBank ID | DB01422 |
| Drug Name | Nitroxoline |
| Target ID | BE0001534 |
| UniProt ID | P50579 |
| Regulation Type | inhibitor |
| PubMed IDs | 21088277 |
| Citations | Shim JS, Matsui Y, Bhat S, Nacev BA, Xu J, Bhang HE, Dhara S, Han KC, Chong CR, Pomper MG, So A, Liu JO: Effect of nitroxoline on angiogenesis and growth of human bladder cancer. J Natl Cancer Inst. 2010 Dec 15;102(24):1855-73. doi: 10.1093/jnci/djq457. Epub 2010 Nov 18. |
| Groups | Experimental |
| Direct Classification | Nitroquinolines and derivatives |
| SMILES | OC1=C2N=CC=CC2=C(C=C1)[N+]([O-])=O |
| Pathways | |
| PharmGKB | PA164754993 |
| ChEMBL | CHEMBL1454910 |
