| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10011321 | HBV | ENSG00000196549.13 | protein_coding | MME | No | No | 4311 | P08473 |
| TVIS10011322 | HBV | ENSG00000196549.13 | protein_coding | MME | No | No | 4311 | P08473 |
| TVIS10032436 | HBV | ENSG00000196549.13 | protein_coding | MME | No | No | 4311 | P08473 |
| TVIS30058704 | HIV | ENSG00000196549.13 | protein_coding | MME | No | No | 4311 | P08473 |
| TVIS30058705 | HIV | ENSG00000196549.13 | protein_coding | MME | No | No | 4311 | P08473 |
| TVIS30058706 | HIV | ENSG00000196549.13 | protein_coding | MME | No | No | 4311 | P08473 |
| TVIS30058707 | HIV | ENSG00000196549.13 | protein_coding | MME | No | No | 4311 | P08473 |
| TVIS30058708 | HIV | ENSG00000196549.13 | protein_coding | MME | No | No | 4311 | P08473 |
| TVIS30058709 | HIV | ENSG00000196549.13 | protein_coding | MME | No | No | 4311 | P08473 |
| TVIS20003440 | HPV | ENSG00000196549.13 | protein_coding | MME | No | No | 4311 | P08473 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | MME |
|---|---|
| DrugBank ID | DB00886 |
| Drug Name | Omapatrilat |
| Target ID | BE0000266 |
| UniProt ID | P08473 |
| Regulation Type | |
| PubMed IDs | 10856267; 10856268; 10933361; 11040230; 11041166 |
| Citations | Intengan HD, Schiffrin EL: Vasopeptidase inhibition has potent effects on blood pressure and resistance arteries in stroke-prone spontaneously hypertensive rats. Hypertension. 2000 Jun;35(6):1221-5.@@Azizi M, Massien C, Michaud A, Corvol P: In vitro and in vivo inhibition of the 2 active sites of ACE by omapatrilat, a vasopeptidase inhibitor. Hypertension. 2000 Jun;35(6):1226-31.@@McClean DR, Ikram H, Garlick AH, Richards AM, Nicholls MG, Crozier IG: The clinical, cardiac, renal, arterial and neurohormonal effects of omapatrilat, a vasopeptidase inhibitor, in patients with chronic heart failure. J Am Coll Cardiol. 2000 Aug;36(2):479-86.@@Troughton RW, Rademaker MT, Powell JD, Yandle TG, Espiner EA, Frampton CM, Nicholls MG, Richards AM: Beneficial renal and hemodynamic effects of omapatrilat in mild and severe heart failure. Hypertension. 2000 Oct;36(4):523-30.@@Burrell LM, Droogh J, Man in't Veld O, Rockell MD, Farina NK, Johnston CI: Antihypertensive and antihypertrophic effects of omapatrilat in SHR. Am J Hypertens. 2000 Oct;13(10):1110-6. |
| Groups | Investigational |
| Direct Classification | Dipeptides |
| SMILES | [H][C@]12CCC[C@H](N1C(=O)[C@H](CCS2)NC(=O)[C@@H](S)CC1=CC=CC=C1)C(O)=O |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL289556 |
