| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20007672 | HPV | ENSG00000262406.3 | protein_coding | MMP12 | No | No | 4321 | P39900 |
| TVIS20012760 | HPV | ENSG00000262406.3 | protein_coding | MMP12 | No | No | 4321 | P39900 |
| TVIS20015907 | HPV | ENSG00000262406.3 | protein_coding | MMP12 | No | No | 4321 | P39900 |
| TVIS20015965 | HPV | ENSG00000262406.3 | protein_coding | MMP12 | No | No | 4321 | P39900 |
| TVIS20015865 | HPV | ENSG00000262406.3 | protein_coding | MMP12 | No | No | 4321 | P39900 |
| TVIS20016346 | HPV | ENSG00000262406.3 | protein_coding | MMP12 | No | No | 4321 | P39900 |
| TVIS20049593 | HPV | ENSG00000262406.3 | protein_coding | MMP12 | No | No | 4321 | P39900 |
| TVIS20013121 | HPV | ENSG00000262406.3 | protein_coding | MMP12 | No | No | 4321 | P39900 |
| TVIS20021282 | HPV | ENSG00000262406.3 | protein_coding | MMP12 | No | No | 4321 | P39900 |
| TVIS20016344 | HPV | ENSG00000262406.3 | protein_coding | MMP12 | No | No | 4321 | P39900 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | MMP12 |
|---|---|
| DrugBank ID | DB00786 |
| Drug Name | Marimastat |
| Target ID | BE0001198 |
| UniProt ID | P39900 |
| Regulation Type | inhibitor |
| PubMed IDs | 10852638; 10669951 |
| Citations | Heath EI, Grochow LB: Clinical potential of matrix metalloprotease inhibitors in cancer therapy. Drugs. 2000 May;59(5):1043-55.@@Belotti D, Paganoni P, Giavazzi R: MMP inhibitors: experimental and clinical studies. Int J Biol Markers. 1999 Oct-Dec;14(4):232-8. |
| Groups | Investigational |
| Direct Classification | Secondary alcohols |
| SMILES | CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](O)C(=O)NO)C(C)(C)C |
| Pathways | |
| PharmGKB | PA164748329 |
| ChEMBL | CHEMBL279785 |
