| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30074144 | HIV | ENSG00000124275.15 | protein_coding | MTRR | No | No | 4552 | Q9UBK8 |
| TVIS30061858 | HIV | ENSG00000124275.15 | protein_coding | MTRR | No | No | 4552 | Q9UBK8 |
| TVIS30061859 | HIV | ENSG00000124275.15 | protein_coding | MTRR | No | No | 4552 | Q9UBK8 |
| TVIS30061860 | HIV | ENSG00000124275.15 | protein_coding | MTRR | No | No | 4552 | Q9UBK8 |
| TVIS30061861 | HIV | ENSG00000124275.15 | protein_coding | MTRR | No | No | 4552 | Q9UBK8 |
| TVIS20068237 | HPV | ENSG00000124275.15 | protein_coding | MTRR | No | No | 4552 | Q9UBK8 |
| TVIS44030127 | HTLV-1 | ENSG00000124275.15 | protein_coding | MTRR | No | No | 4552 | Q9UBK8 |
| TVIS44014688 | HTLV-1 | ENSG00000124275.15 | protein_coding | MTRR | No | No | 4552 | Q9UBK8 |
| TVIS44003968 | HTLV-1 | ENSG00000124275.15 | protein_coding | MTRR | No | No | 4552 | Q9UBK8 |
| TVIS44050471 | HTLV-1 | ENSG00000124275.15 | protein_coding | MTRR | No | No | 4552 | Q9UBK8 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | MTRR |
|---|---|
| DrugBank ID | DB00134 |
| Drug Name | Methionine |
| Target ID | BE0000763 |
| UniProt ID | Q9UBK8 |
| Regulation Type | product of |
| PubMed IDs | 17079868; 17101561; 17369066 |
| Citations | Kim DJ, Park BL, Koh JM, Kim GS, Kim LH, Cheong HS, Shin HD, Hong JM, Kim TH, Shin HI, Park EK, Kim SY: Methionine synthase reductase polymorphisms are associated with serum osteocalcin levels in postmenopausal women. Exp Mol Med. 2006 Oct 31;38(5):519-24.@@Tvedegaard KC, Rudiger NS, Pedersen BN, Moller J: Detection of MTRR 66A-->G polymorphism using the real-time polymerase chain reaction machine LightCycler for determination of composition of allele after restriction cleavage. Scand J Clin Lab Invest. 2006;66(8):685-93.@@Elmore CL, Wu X, Leclerc D, Watson ED, Bottiglieri T, Krupenko NI, Krupenko SA, Cross JC, Rozen R, Gravel RA, Matthews RG: Metabolic derangement of methionine and folate metabolism in mice deficient in methionine synthase reductase. Mol Genet Metab. 2007 May;91(1):85-97. Epub 2007 Mar 21. |
| Groups | Approved; Nutraceutical |
| Direct Classification | Methionine and derivatives |
| SMILES | CSCC[C@H](N)C(O)=O |
| Pathways | Demeclocycline Action Pathway; Spermidine and Spermine Biosynthesis; Lincomycin Action Pathway; Gentamicin Action Pathway; Josamycin Action Pathway; Methionine Adenosyltransferase Deficiency; Methacycline Action Pathway; Non-Ketotic Hyperglycinemia; Clarithromycin Action Pathway; Betaine Metabolism; Paromomycin Action Pathway; Minocycline Action Pathway; Lymecycline Action Pathway; Glycine and Serine Metabolism; Troleandomycin Action Pathway; Amikacin Action Pathway; Oxytetracycline Action Pathway; Tetracycline Action Pathway; Methionine Metabolism; Spectinomycin Action Pathway; Doxycycline Action Pathway; Dihydropyrimidine Dehydrogenase Deficiency (DHPD); Cystathionine beta-Synthase Deficiency; Telithromycin Action Pathway; Roxithromycin Action Pathway; Tigecycline Action Pathway; Sarcosine Oncometabolite Pathway; Sarcosinemia; Arbekacin Action Pathway; Chloramphenicol Action Pathway |
| PharmGKB | PA450423 |
| ChEMBL | CHEMBL42336 |
