Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS46000368BKPyvENSG00000138823.14protein_codingMTTPNoNo4547E9PBP6
P55157
TVIS30060587HIVENSG00000138823.14protein_codingMTTPNoNo4547E9PBP6
P55157
TVIS20058865HPVENSG00000138823.14protein_codingMTTPNoNo4547E9PBP6
P55157
TCGA Plot Options
Drug Information
GeneMTTP
DrugBank IDDB04852
Drug NameImplitapide
Target IDBE0000232
UniProt IDP55157
Regulation Type
PubMed IDs15684478
CitationsUeshima K, Akihisa-Umeno H, Nagayoshi A, Takakura S, Matsuo M, Mutoh S: Implitapide, a microsomal triglyceride transfer protein inhibitor, reduces progression of atherosclerosis in apolipoprotein E knockout mice fed a Western-type diet: involvement of the inhibition of postprandial triglyceride elevation. Biol Pharm Bull. 2005 Feb;28(2):247-52.
GroupsInvestigational
Direct ClassificationAlpha carbolines
SMILESCC1=NC2=C(C3=CC=CC=C3N2CC2=CC(=CC=C2)[C@H](C2CCCC2)C(=O)N[C@@H](CO)C2=CC=CC=C2)C(C)=C1
Pathways
PharmGKB
ChEMBLCHEMBL2105804