VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
---|---|---|---|---|---|---|---|---|
TVIS46000368 | BKPyv | ENSG00000138823.14 | protein_coding | MTTP | No | No | 4547 | E9PBP6 P55157 |
TVIS30060587 | HIV | ENSG00000138823.14 | protein_coding | MTTP | No | No | 4547 | E9PBP6 P55157 |
TVIS20058865 | HPV | ENSG00000138823.14 | protein_coding | MTTP | No | No | 4547 | E9PBP6 P55157 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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Gene | MTTP |
---|---|
DrugBank ID | DB05678 |
Drug Name | SLx-4090 |
Target ID | BE0000232 |
UniProt ID | P55157 |
Regulation Type | inhibitor |
PubMed IDs | 21406547 |
Citations | Kim E, Campbell S, Schueller O, Wong E, Cole B, Kuo J, Ellis J, Ferkany J, Sweetnam P: A small-molecule inhibitor of enterocytic microsomal triglyceride transfer protein, SLx-4090: biochemical, pharmacodynamic, pharmacokinetic, and safety profile. J Pharmacol Exp Ther. 2011 Jun;337(3):775-85. doi: 10.1124/jpet.110.177527. Epub 2011 Mar 15. |
Groups | Investigational |
Direct Classification | |
SMILES | COC1=CC=CC(C(=O)NC2=CC3=C(CN(CC3)C(=O)OC3=CC=CC=C3)C=C2)=C1C1=CC=C(C=C1)C(F)(F)F |
Pathways | |
PharmGKB | |
ChEMBL |