| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10009296 | HBV | ENSG00000143257.12 | protein_coding | NR1I3 | No | No | 9970 | F1DAL4 Q14994 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | NR1I3 |
|---|---|
| DrugBank ID | DB00737 |
| Drug Name | Meclizine |
| Target ID | BE0003848 |
| UniProt ID | Q14994 |
| Regulation Type | inverse agonist |
| PubMed IDs | 15272053 |
| Citations | Huang W, Zhang J, Wei P, Schrader WT, Moore DD: Meclizine is an agonist ligand for mouse constitutive androstane receptor (CAR) and an inverse agonist for human CAR. Mol Endocrinol. 2004 Oct;18(10):2402-8. Epub 2004 Jul 22. |
| Groups | Approved |
| Direct Classification | Diphenylmethanes |
| SMILES | CC1=CC(CN2CCN(CC2)C(C2=CC=CC=C2)C2=CC=C(Cl)C=C2)=CC=C1 |
| Pathways | Meclizine H1-Antihistamine Action |
| PharmGKB | PA450338 |
| ChEMBL | CHEMBL1623 |
