| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44045412 | HTLV-1 | ENSG00000112541.19 | protein_coding | PDE10A | No | No | 10846 | A0A1B1UZR0 Q9Y233 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PDE10A |
|---|---|
| DrugBank ID | DB01113 |
| Drug Name | Papaverine |
| Target ID | BE0000631 |
| UniProt ID | Q9Y233 |
| Regulation Type | inhibitor |
| PubMed IDs | 19066855 |
| Citations | Weber M, Breier M, Ko D, Thangaraj N, Marzan DE, Swerdlow NR: Evaluating the antipsychotic profile of the preferential PDE10A inhibitor, papaverine. Psychopharmacology (Berl). 2009 May;203(4):723-35. doi: 10.1007/s00213-008-1419-x. Epub 2008 Dec 9. |
| Groups | Approved; Investigational |
| Direct Classification | Benzylisoquinolines |
| SMILES | COC1=C(OC)C=C(CC2=NC=CC3=CC(OC)=C(OC)C=C23)C=C1 |
| Pathways | |
| PharmGKB | PA164745550 |
| ChEMBL | CHEMBL19224 |
