| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30062310 | HIV | ENSG00000113448.21 | protein_coding | PDE4D | No | No | 5144 | A0A140VJR0 Q08499 |
| TVIS30062311 | HIV | ENSG00000113448.21 | protein_coding | PDE4D | No | No | 5144 | A0A140VJR0 Q08499 |
| TVIS30062312 | HIV | ENSG00000113448.21 | protein_coding | PDE4D | No | No | 5144 | A0A140VJR0 Q08499 |
| TVIS30062313 | HIV | ENSG00000113448.21 | protein_coding | PDE4D | No | No | 5144 | A0A140VJR0 Q08499 |
| TVIS30062314 | HIV | ENSG00000113448.21 | protein_coding | PDE4D | No | No | 5144 | A0A140VJR0 Q08499 |
| TVIS20001830 | HPV | ENSG00000113448.21 | protein_coding | PDE4D | No | No | 5144 | A0A140VJR0 Q08499 |
| TVIS20001312 | HPV | ENSG00000113448.21 | protein_coding | PDE4D | No | No | 5144 | A0A140VJR0 Q08499 |
| TVIS20001313 | HPV | ENSG00000113448.21 | protein_coding | PDE4D | No | No | 5144 | A0A140VJR0 Q08499 |
| TVIS20006556 | HPV | ENSG00000113448.21 | protein_coding | PDE4D | No | No | 5144 | A0A140VJR0 Q08499 |
| TVIS20008253 | HPV | ENSG00000113448.21 | protein_coding | PDE4D | No | No | 5144 | A0A140VJR0 Q08499 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PDE4D |
|---|---|
| DrugBank ID | DB00651 |
| Drug Name | Dyphylline |
| Target ID | BE0001287 |
| UniProt ID | Q08499 |
| Regulation Type | inhibitor |
| PubMed IDs | 17139284; 17016423; 7925603 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Hariton C: Ocular hypotension induced by topical dopaminergic drugs and phosphodiesterase inhibitors. Eur J Pharmacol. 1994 Jun 2;258(1-2):85-94. |
| Groups | Approved |
| Direct Classification | Xanthines |
| SMILES | CN1C2=C(N(CC(O)CO)C=N2)C(=O)N(C)C1=O |
| Pathways | |
| PharmGKB | PA164748027 |
| ChEMBL | CHEMBL1752 |
