| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30068861 | HIV | ENSG00000104368.19 | protein_coding | PLAT | No | No | 5327 | B4DN26 P00750 |
| TVIS44009042 | HTLV-1 | ENSG00000104368.19 | protein_coding | PLAT | No | No | 5327 | B4DN26 P00750 |
| TVIS44016935 | HTLV-1 | ENSG00000104368.19 | protein_coding | PLAT | No | No | 5327 | B4DN26 P00750 |
| TVIS44019982 | HTLV-1 | ENSG00000104368.19 | protein_coding | PLAT | No | No | 5327 | B4DN26 P00750 |
| TVIS44049186 | HTLV-1 | ENSG00000104368.19 | protein_coding | PLAT | No | No | 5327 | B4DN26 P00750 |
| TVIS44045927 | HTLV-1 | ENSG00000104368.19 | protein_coding | PLAT | No | No | 5327 | B4DN26 P00750 |
| TVIS44045926 | HTLV-1 | ENSG00000104368.19 | protein_coding | PLAT | No | No | 5327 | B4DN26 P00750 |
| TVIS44045925 | HTLV-1 | ENSG00000104368.19 | protein_coding | PLAT | No | No | 5327 | B4DN26 P00750 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PLAT |
|---|---|
| DrugBank ID | DB01088 |
| Drug Name | Iloprost |
| Target ID | BE0001088 |
| UniProt ID | P00750 |
| Regulation Type | other/unknown |
| PubMed IDs | 1370924; 1689620; 1717784; 1726988; 17510465 |
| Citations | Kerins DM, Roy L, Kunitada S, Adedoyin A, FitzGerald GA, Fitzgerald DJ: Pharmacokinetics of tissue-type plasminogen activator during acute myocardial infarction in men. Effect of a prostacyclin analogue. Circulation. 1992 Feb;85(2):526-32.@@Nicolini FA, Mehta JL, Nichols WW, Saldeen TG, Grant M: Prostacyclin analogue iloprost decreases thrombolytic potential of tissue-type plasminogen activator in canine coronary thrombosis. Circulation. 1990 Mar;81(3):1115-22.@@Nichols WW, Nicolini FA, Saldeen TG, Mehta JL: Combined thrombolytic effects of tissue-plasminogen activator and a fibrinogen-degradation product peptide 6A or iloprost. J Cardiovasc Pharmacol. 1991 Aug;18(2):231-6.@@Nizankowski R, Krzanowski M, Musial J, Szczeklik A: [Effect of thromboxane A2 synthetase inhibitor and prostacyclin analogue on arterial blood pressure, fibrinolysis and platelet function in patients with hypertension]. Pol Tyg Lek. 1991 Jan 7-14;46(1-3):18-21.@@Herczenik E, Bouma B, Korporaal SJ, Strangi R, Zeng Q, Gros P, Van Eck M, Van Berkel TJ, Gebbink MF, Akkerman JW: Activation of human platelets by misfolded proteins. Arterioscler Thromb Vasc Biol. 2007 Jul;27(7):1657-65. Epub 2007 May 17. |
| Groups | Approved; Investigational |
| Direct Classification | Prostaglandins and related compounds |
| SMILES | [H][C@]12C[C@@H](O)[C@H](C=C[C@@H](O)C(C)CC#CC)[C@@]1([H])CC(C2)=CCCCC(O)=O |
| Pathways | |
| PharmGKB | PA164746843 |
| ChEMBL | CHEMBL494 |
