| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30068861 | HIV | ENSG00000104368.19 | protein_coding | PLAT | No | No | 5327 | B4DN26 P00750 |
| TVIS44009042 | HTLV-1 | ENSG00000104368.19 | protein_coding | PLAT | No | No | 5327 | B4DN26 P00750 |
| TVIS44016935 | HTLV-1 | ENSG00000104368.19 | protein_coding | PLAT | No | No | 5327 | B4DN26 P00750 |
| TVIS44019982 | HTLV-1 | ENSG00000104368.19 | protein_coding | PLAT | No | No | 5327 | B4DN26 P00750 |
| TVIS44049186 | HTLV-1 | ENSG00000104368.19 | protein_coding | PLAT | No | No | 5327 | B4DN26 P00750 |
| TVIS44045927 | HTLV-1 | ENSG00000104368.19 | protein_coding | PLAT | No | No | 5327 | B4DN26 P00750 |
| TVIS44045926 | HTLV-1 | ENSG00000104368.19 | protein_coding | PLAT | No | No | 5327 | B4DN26 P00750 |
| TVIS44045925 | HTLV-1 | ENSG00000104368.19 | protein_coding | PLAT | No | No | 5327 | B4DN26 P00750 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | PLAT |
|---|---|
| DrugBank ID | DB00513 |
| Drug Name | Aminocaproic acid |
| Target ID | BE0001088 |
| UniProt ID | P00750 |
| Regulation Type | antagonist |
| PubMed IDs | 2502209; 3146348; 7962113; 8073394 |
| Citations | Husain SS, Hasan AA, Budzynski AZ: Differences between binding of one-chain and two-chain tissue plasminogen activators to non-cross-linked and cross-linked fibrin clots. Blood. 1989 Aug 15;74(3):999-1006.@@Urano T, Sator de Serrano V, Gaffney PJ, Castellino FJ: Effectors of the activation of human [Glu1]plasminogen by human tissue plasminogen activator. Biochemistry. 1988 Aug 23;27(17):6522-8.@@Tran-Thang C, Vouillamoz D, Kruithof EK, Sordat B: Human Co115 colon carcinoma cells potentiate the degradation of laminin mediated by tissue-type plasminogen activator. J Cell Physiol. 1994 Nov;161(2):285-92.@@Krishnamurti C, Vukelja SJ, Alving BM: Inhibitory effects of lysine analogues on t-PA induced whole blood clot lysis. Thromb Res. 1994 Mar 15;73(6):419-30. |
| Groups | Approved; Investigational |
| Direct Classification | Medium-chain fatty acids |
| SMILES | NCCCCCC(O)=O |
| Pathways | Aminocaproic Acid Action Pathway |
| PharmGKB | PA164774947 |
| ChEMBL | CHEMBL1046 |
