| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30088922 | HIV | ENSG00000011422.12 | protein_coding | PLAUR | No | No | 5329 | M0R1I2 Q03405 |
| TVIS44047929 | HTLV-1 | ENSG00000011422.12 | protein_coding | PLAUR | No | No | 5329 | M0R1I2 Q03405 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PLAUR |
|---|---|
| DrugBank ID | DB00031 |
| Drug Name | Tenecteplase |
| Target ID | BE0000717 |
| UniProt ID | Q03405 |
| Regulation Type | |
| PubMed IDs | 15231724; 11447759; 12210068 |
| Citations | Maupas-Schwalm F, Auge N, Robinet C, Cambus JP, Parsons SJ, Salvayre R, Negre-Salvayre A: The sphingomyelin/ceramide pathway is involved in ERK1/2 phosphorylation, cell proliferation, and uPAR overexpression induced by tissue-type plasminogen activator. FASEB J. 2004 Sep;18(12):1398-400. Epub 2004 Jul 1.@@Bankl HC, Samorapoompichit P, Pikula B, Latinovic L, Bankl H, Lechner K, Valent P: Characterization of human prostate mast cells and their increase in periprostatic vein thrombosis. Am J Clin Pathol. 2001 Jul;116(1):97-106.@@Ferrier CM, Van Geloof WL, Straatman H, Van De Molengraft FJ, Van Muijen GN, Ruiter DJ: Spitz naevi may express components of the plasminogen activation system. J Pathol. 2002 Sep;198(1):92-9. |
| Groups | Approved |
| Direct Classification | Peptides |
| SMILES | |
| Pathways | Tenecteplase Action Pathway |
| PharmGKB | PA164776757 |
| ChEMBL | CHEMBL2108791 |