Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS30088922HIVENSG00000011422.12protein_codingPLAURNoNo5329M0R1I2
Q03405
TVIS44047929HTLV-1ENSG00000011422.12protein_codingPLAURNoNo5329M0R1I2
Q03405
TCGA Plot Options
Drug Information
GenePLAUR
DrugBank IDDB00031
Drug NameTenecteplase
Target IDBE0000717
UniProt IDQ03405
Regulation Type
PubMed IDs15231724; 11447759; 12210068
CitationsMaupas-Schwalm F, Auge N, Robinet C, Cambus JP, Parsons SJ, Salvayre R, Negre-Salvayre A: The sphingomyelin/ceramide pathway is involved in ERK1/2 phosphorylation, cell proliferation, and uPAR overexpression induced by tissue-type plasminogen activator. FASEB J. 2004 Sep;18(12):1398-400. Epub 2004 Jul 1.@@Bankl HC, Samorapoompichit P, Pikula B, Latinovic L, Bankl H, Lechner K, Valent P: Characterization of human prostate mast cells and their increase in periprostatic vein thrombosis. Am J Clin Pathol. 2001 Jul;116(1):97-106.@@Ferrier CM, Van Geloof WL, Straatman H, Van De Molengraft FJ, Van Muijen GN, Ruiter DJ: Spitz naevi may express components of the plasminogen activation system. J Pathol. 2002 Sep;198(1):92-9.
GroupsApproved
Direct ClassificationPeptides
SMILES
PathwaysTenecteplase Action Pathway
PharmGKBPA164776757
ChEMBLCHEMBL2108791