Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS30013537HIVENSG00000196262.15protein_codingPPIANoNo5478P62937
TVIS30067103HIVENSG00000196262.15protein_codingPPIANoNo5478P62937
TCGA Plot Options
Drug Information
GenePPIA
DrugBank IDDB00172
Drug NameProline
Target IDBE0001014
UniProt IDP62937
Regulation Typebinder
PubMed IDs17139284; 17016423; 11752352
CitationsOverington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5.
GroupsNutraceutical
Direct ClassificationProline and derivatives
SMILESOC(=O)[C@@H]1CCCN1
PathwaysClomocycline Action Pathway; The Oncogenic Action of Succinate; Guanidinoacetate Methyltransferase Deficiency (GAMT Deficiency); Rolitetracycline Action Pathway; Hyperornithinemia with Gyrate Atrophy (HOGA); Josamycin Action Pathway; Kanamycin Action Pathway; Gentamicin Action Pathway; Tobramycin Action Pathway; The Oncogenic Action of Fumarate; Azithromycin Action Pathway; Hyperprolinemia Type II; Clindamycin Action Pathway; Clarithromycin Action Pathway; L-Arginine:Glycine Amidinotransferase Deficiency; Arginine: Glycine Amidinotransferase Deficiency (AGAT Deficiency); Prolidase Deficiency (PD); Troleandomycin Action Pathway; Creatine Deficiency, Guanidinoacetate Methyltransferase Deficiency; Oxytetracycline Action Pathway; Tetracycline Action Pathway; Erythromycin Action Pathway; Netilmicin Action Pathway; Hyperprolinemia Type I; Neomycin Action Pathway; Roxithromycin Action Pathway; Arginine and Proline Metabolism; Prolinemia Type II; Arbekacin Action Pathway; Streptomycin Action Pathway
PharmGKBPA451125
ChEMBLCHEMBL54922