| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44006316 | HTLV-1 | ENSG00000184500.16 | protein_coding | PROS1 | No | No | 5627 | A0A0S2Z4K3 A0A0S2Z4L3 P07225 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PROS1 |
|---|---|
| DrugBank ID | DB00170 |
| Drug Name | Menadione |
| Target ID | BE0000943 |
| UniProt ID | P07225 |
| Regulation Type | activator |
| PubMed IDs | 8161215; 12033454 |
| Citations | Chai YC, Hendrich S, Thomas JA: Protein S-thiolation in hepatocytes stimulated by t-butyl hydroperoxide, menadione, and neutrophils. Arch Biochem Biophys. 1994 Apr;310(1):264-72.@@Mallis RJ, Hamann MJ, Zhao W, Zhang T, Hendrich S, Thomas JA: Irreversible thiol oxidation in carbonic anhydrase III: protection by S-glutathiolation and detection in aging rats. Biol Chem. 2002 Mar-Apr;383(3-4):649-62. |
| Groups | Approved; Nutraceutical |
| Direct Classification | Naphthoquinones |
| SMILES | CC1=CC(=O)C2=CC=CC=C2C1=O |
| Pathways | |
| PharmGKB | PA450358 |
| ChEMBL | CHEMBL590 |
