| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10006300 | HBV | ENSG00000184500.16 | protein_coding | PROS1 | No | No | 5627 | A0A0S2Z4K3 A0A0S2Z4L3 P07225 |
| TVIS44001630 | HTLV-1 | ENSG00000184500.16 | protein_coding | PROS1 | No | No | 5627 | A0A0S2Z4K3 A0A0S2Z4L3 P07225 |
| TVIS44012101 | HTLV-1 | ENSG00000184500.16 | protein_coding | PROS1 | No | No | 5627 | A0A0S2Z4K3 A0A0S2Z4L3 P07225 |
| TVIS44025142 | HTLV-1 | ENSG00000184500.16 | protein_coding | PROS1 | No | No | 5627 | A0A0S2Z4K3 A0A0S2Z4L3 P07225 |
| TVIS44019178 | HTLV-1 | ENSG00000184500.16 | protein_coding | PROS1 | No | No | 5627 | A0A0S2Z4K3 A0A0S2Z4L3 P07225 |
| TVIS44019179 | HTLV-1 | ENSG00000184500.16 | protein_coding | PROS1 | No | No | 5627 | A0A0S2Z4K3 A0A0S2Z4L3 P07225 |
| TVIS44019180 | HTLV-1 | ENSG00000184500.16 | protein_coding | PROS1 | No | No | 5627 | A0A0S2Z4K3 A0A0S2Z4L3 P07225 |
| TVIS44031402 | HTLV-1 | ENSG00000184500.16 | protein_coding | PROS1 | No | No | 5627 | A0A0S2Z4K3 A0A0S2Z4L3 P07225 |
| TVIS44013665 | HTLV-1 | ENSG00000184500.16 | protein_coding | PROS1 | No | No | 5627 | A0A0S2Z4K3 A0A0S2Z4L3 P07225 |
| TVIS44032135 | HTLV-1 | ENSG00000184500.16 | protein_coding | PROS1 | No | No | 5627 | A0A0S2Z4K3 A0A0S2Z4L3 P07225 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PROS1 |
|---|---|
| DrugBank ID | DB00055 |
| Drug Name | Drotrecogin alfa |
| Target ID | BE0000943 |
| UniProt ID | P07225 |
| Regulation Type | |
| PubMed IDs | 12062545; 1828915; 3160800 |
| Citations | Cvirn G, Gallistl S, Koestenberger M, Kutschera J, Leschnik B, Muntean W: Alpha 2-macroglobulin enhances prothrombin activation and thrombin potential by inhibiting the anticoagulant protein C/protein S system in cord and adult plasma. Thromb Res. 2002 Mar 1;105(5):433-9.@@Hesselvik JF, Malm J, Dahlback B, Blomback M: Protein C, protein S and C4b-binding protein in severe infection and septic shock. Thromb Haemost. 1991 Feb 12;65(2):126-9.@@Cosio FG, Harker C, Batard MA, Brandt JT, Griffin JH: Plasma concentrations of the natural anticoagulants protein C and protein S in patients with proteinuria. J Lab Clin Med. 1985 Aug;106(2):218-22. |
| Groups | Approved; Investigational; Withdrawn |
| Direct Classification | Peptides |
| SMILES | |
| Pathways | |
| PharmGKB | PA131548935 |
| ChEMBL |
