| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30079475 | HIV | ENSG00000124212.6 | protein_coding | PTGIS | No | No | 5740 | Q16647 |
| TVIS20001251 | HPV | ENSG00000124212.6 | protein_coding | PTGIS | No | No | 5740 | Q16647 |
| TVIS44021396 | HTLV-1 | ENSG00000124212.6 | protein_coding | PTGIS | No | No | 5740 | Q16647 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PTGIS |
|---|---|
| DrugBank ID | DB01240 |
| Drug Name | Epoprostenol |
| Target ID | BE0000117 |
| UniProt ID | Q16647 |
| Regulation Type | inducer |
| PubMed IDs | 20357747; 18081314 |
| Citations | Nakayama T: Genetic polymorphisms of prostacyclin synthase gene and cardiovascular disease. Int Angiol. 2010 Apr;29(2 Suppl):33-42.@@Ruan KH, Wu J, Cervantes V: Characterization of the substrate mimic bound to engineered prostacyclin synthase in solution using high-resolution NMR spectroscopy and mutagenesis: implication of the molecular mechanism in biosynthesis of prostacyclin. Biochemistry. 2008 Jan 15;47(2):680-8. Epub 2007 Dec 15. |
| Groups | Approved |
| Direct Classification | |
| SMILES | [H][C@]12C[C@@H](O)[C@H](C=C[C@@H](O)CCCCC)[C@@]1([H])CC(O2)=CCCCC(O)=O |
| Pathways | |
| PharmGKB | PA449479 |
| ChEMBL | CHEMBL1139 |
