| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44044651 | HTLV-1 | ENSG00000077092.20 | protein_coding | RARB | No | No | 5915 | P10826 Q5QHG3 Q86UC5 |
| TVIS44048782 | HTLV-1 | ENSG00000077092.20 | protein_coding | RARB | No | No | 5915 | P10826 Q5QHG3 Q86UC5 |
| TVIS44036417 | HTLV-1 | ENSG00000077092.20 | protein_coding | RARB | No | No | 5915 | P10826 Q5QHG3 Q86UC5 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | RARB |
|---|---|
| DrugBank ID | DB00459 |
| Drug Name | Acitretin |
| Target ID | BE0000206 |
| UniProt ID | P10826 |
| Regulation Type | agonist |
| PubMed IDs | 7755585; 11586072; 19144697 |
| Citations | Berggren Soderlund M, Johannesson G, Fex G: Expression of human all-trans-retinoic acid receptor beta and its ligand-binding domain in Escherichia coli. Biochem J. 1995 May 15;308 ( Pt 1):353-9.@@Zouboulis CC: Retinoids--which dermatological indications will benefit in the near future? Skin Pharmacol Appl Skin Physiol. 2001 Sep-Oct;14(5):303-15.@@Tippmann F, Hundt J, Schneider A, Endres K, Fahrenholz F: Up-regulation of the alpha-secretase ADAM10 by retinoic acid receptors and acitretin. FASEB J. 2009 Jun;23(6):1643-54. doi: 10.1096/fj.08-121392. Epub 2009 Jan 14. |
| Groups | Approved |
| Direct Classification | Retinoids |
| SMILES | COC1=C(C)C(C)=C(C=CC(C)=CC=CC(C)=CC(O)=O)C(C)=C1 |
| Pathways | |
| PharmGKB | PA448039 |
| ChEMBL | CHEMBL1131 |
