| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44044651 | HTLV-1 | ENSG00000077092.20 | protein_coding | RARB | No | No | 5915 | P10826 Q5QHG3 Q86UC5 |
| TVIS44048782 | HTLV-1 | ENSG00000077092.20 | protein_coding | RARB | No | No | 5915 | P10826 Q5QHG3 Q86UC5 |
| TVIS44036417 | HTLV-1 | ENSG00000077092.20 | protein_coding | RARB | No | No | 5915 | P10826 Q5QHG3 Q86UC5 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | RARB |
|---|---|
| DrugBank ID | DB00755 |
| Drug Name | Tretinoin |
| Target ID | BE0000206 |
| UniProt ID | P10826 |
| Regulation Type | agonist |
| PubMed IDs | 15958702; 9160172 |
| Citations | Steidl U, Schroeder T, Steidl C, Kobbe G, Graef T, Bork S, Pechtel S, Kliszewski S, Kuendgen A, Rohr UP, Fenk R, Schroeder M, Haase D, Haas R, Kronenwett R: Distinct gene expression pattern of malignant hematopoietic stem and progenitor cells in polycythemia vera. Ann N Y Acad Sci. 2005 Jun;1044:94-108.@@Regazzi MB, Iacona I, Gervasutti C, Lazzarino M, Toma S: Clinical pharmacokinetics of tretinoin. Clin Pharmacokinet. 1997 May;32(5):382-402. doi: 10.2165/00003088-199732050-00004. |
| Groups | Approved; Investigational; Nutraceutical |
| Direct Classification | |
| SMILES | CC(C=CC1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(O)=O |
| Pathways | Retinol Metabolism; Vitamin A Deficiency |
| PharmGKB | PA164746900 |
| ChEMBL | CHEMBL38 |
