Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS44031876HTLV-1ENSG00000136531.19protein_codingSCN2ANoNo6326Q99250
TCGA Plot Options
Drug Information
GeneSCN2A
DrugBank IDDB00252
Drug NamePhenytoin
Target IDBE0002081
UniProt IDQ99250
Regulation Typeinhibitor
PubMed IDs15805193
CitationsTate SK, Depondt C, Sisodiya SM, Cavalleri GL, Schorge S, Soranzo N, Thom M, Sen A, Shorvon SD, Sander JW, Wood NW, Goldstein DB: Genetic predictors of the maximum doses patients receive during clinical use of the anti-epileptic drugs carbamazepine and phenytoin. Proc Natl Acad Sci U S A. 2005 Apr 12;102(15):5507-12. Epub 2005 Apr 1.
GroupsApproved; Vet_approved
Direct ClassificationPhenylhydantoins
SMILESO=C1NC(=O)C(N1)(C1=CC=CC=C1)C1=CC=CC=C1
PathwaysFosphenytoin (Antiarrhythmic) Action Pathway; Fosphenytoin (Antiarrhythmic) Metabolism Pathway; Phenytoin (Antiarrhythmic) Action Pathway
PharmGKBPA450947
ChEMBLCHEMBL16