| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30051609 | HIV | ENSG00000136531.19 | protein_coding | SCN2A | No | No | 6326 | Q99250 |
| TVIS30051610 | HIV | ENSG00000136531.19 | protein_coding | SCN2A | No | No | 6326 | Q99250 |
| TVIS30051611 | HIV | ENSG00000136531.19 | protein_coding | SCN2A | No | No | 6326 | Q99250 |
| TVIS30051612 | HIV | ENSG00000136531.19 | protein_coding | SCN2A | No | No | 6326 | Q99250 |
| TVIS30051613 | HIV | ENSG00000136531.19 | protein_coding | SCN2A | No | No | 6326 | Q99250 |
| TVIS30051614 | HIV | ENSG00000136531.19 | protein_coding | SCN2A | No | No | 6326 | Q99250 |
| TVIS20016115 | HPV | ENSG00000136531.19 | protein_coding | SCN2A | No | No | 6326 | Q99250 |
| TVIS20016145 | HPV | ENSG00000136531.19 | protein_coding | SCN2A | No | No | 6326 | Q99250 |
| TVIS20016114 | HPV | ENSG00000136531.19 | protein_coding | SCN2A | No | No | 6326 | Q99250 |
| TVIS20016127 | HPV | ENSG00000136531.19 | protein_coding | SCN2A | No | No | 6326 | Q99250 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | SCN2A |
|---|---|
| DrugBank ID | DB00193 |
| Drug Name | Tramadol |
| Target ID | BE0002081 |
| UniProt ID | Q99250 |
| Regulation Type | inhibitor |
| PubMed IDs | 16949748; 31004280 |
| Citations | Haeseler G, Foadi N, Ahrens J, Dengler R, Hecker H, Leuwer M: Tramadol, fentanyl and sufentanil but not morphine block voltage-operated sodium channels. Pain. 2006 Dec 15;126(1-3):234-44. doi: 10.1016/j.pain.2006.07.003. Epub 2006 Sep 1.@@Barakat A: Revisiting Tramadol: A Multi-Modal Agent for Pain Management. CNS Drugs. 2019 May;33(5):481-501. doi: 10.1007/s40263-019-00623-5. |
| Groups | Approved; Investigational |
| Direct Classification | |
| SMILES | COC1=CC=CC(=C1)C1(O)CCCCC1CN(C)C |
| Pathways | Tramadol Metabolism Pathway; Tramadol Action Action Pathway |
| PharmGKB | PA451735 |
| ChEMBL | CHEMBL1237044 |
