Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS30064288HIVENSG00000124523.17protein_codingSIRT5NoNo23408Q9NXA8
TVIS30017750HIVENSG00000124523.17protein_codingSIRT5NoNo23408Q9NXA8
TCGA Plot Options
Drug Information
GeneSIRT5
DrugBank IDDB02701
Drug NameNicotinamide
Target IDBE0003362
UniProt IDQ9NXA8
Regulation Type
PubMed IDs17139284; 17016423; 10592235
CitationsOverington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
GroupsApproved; Investigational
Direct ClassificationNicotinamides
SMILESNC(=O)C1=CC=CN=C1
PathwaysNicotinate and Nicotinamide Metabolism
PharmGKB
ChEMBLCHEMBL1140