| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30064288 | HIV | ENSG00000124523.17 | protein_coding | SIRT5 | No | No | 23408 | Q9NXA8 |
| TVIS30017750 | HIV | ENSG00000124523.17 | protein_coding | SIRT5 | No | No | 23408 | Q9NXA8 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | SIRT5 |
|---|---|
| DrugBank ID | DB15493 |
| Drug Name | Cambinol |
| Target ID | BE0003362 |
| UniProt ID | Q9NXA8 |
| Regulation Type | inhibitor |
| PubMed IDs | 16618762 |
| Citations | Heltweg B, Gatbonton T, Schuler AD, Posakony J, Li H, Goehle S, Kollipara R, Depinho RA, Gu Y, Simon JA, Bedalov A: Antitumor activity of a small-molecule inhibitor of human silent information regulator 2 enzymes. Cancer Res. 2006 Apr 15;66(8):4368-77. doi: 10.1158/0008-5472.CAN-05-3617. |
| Groups | Experimental |
| Direct Classification | |
| SMILES | OC1=C(CC2=C(NC(=S)NC2=O)C2=CC=CC=C2)C2=CC=CC=C2C=C1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL491960 |
