| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10009017 | HBV | ENSG00000106688.12 | protein_coding | SLC1A1 | No | No | 6505 | P43005 |
| TVIS10012063 | HBV | ENSG00000106688.12 | protein_coding | SLC1A1 | No | No | 6505 | P43005 |
| TVIS10012064 | HBV | ENSG00000106688.12 | protein_coding | SLC1A1 | No | No | 6505 | P43005 |
| TVIS10038252 | HBV | ENSG00000106688.12 | protein_coding | SLC1A1 | No | No | 6505 | P43005 |
| TVIS30074082 | HIV | ENSG00000106688.12 | protein_coding | SLC1A1 | No | No | 6505 | P43005 |
| TVIS30070672 | HIV | ENSG00000106688.12 | protein_coding | SLC1A1 | No | No | 6505 | P43005 |
| TVIS20033303 | HPV | ENSG00000106688.12 | protein_coding | SLC1A1 | No | No | 6505 | P43005 |
| TVIS44030674 | HTLV-1 | ENSG00000106688.12 | protein_coding | SLC1A1 | No | No | 6505 | P43005 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | SLC1A1 |
|---|---|
| DrugBank ID | DB00142 |
| Drug Name | Glutamic acid |
| Target ID | BE0001054 |
| UniProt ID | P43005 |
| Regulation Type | |
| PubMed IDs | 16831195; 17382927; 17389249; 16959378 |
| Citations | Menaker D, Bendahan A, Kanner BI: The substrate specificity of a neuronal glutamate transporter is determined by the nature of the coupling ion. J Neurochem. 2006 Oct;99(1):20-8. Epub 2006 Jul 11.@@Yun JY, Park KS, Kim JH, Do SH, Zuo Z: Propofol reverses oxidative stress-attenuated glutamate transporter EAAT3 activity: evidence of protein kinase C involvement. Eur J Pharmacol. 2007 Jun 22;565(1-3):83-8. Epub 2007 Mar 3.@@Tao Z, Grewer C: Cooperation of the conserved aspartate 439 and bound amino acid substrate is important for high-affinity Na+ binding to the glutamate transporter EAAC1. J Gen Physiol. 2007 Apr;129(4):331-44.@@Nickell J, Salvatore MF, Pomerleau F, Apparsundaram S, Gerhardt GA: Reduced plasma membrane surface expression of GLAST mediates decreased glutamate regulation in the aged striatum. Neurobiol Aging. 2007 Nov;28(11):1737-48. Epub 2006 Sep 7. |
| Groups | Approved; Nutraceutical |
| Direct Classification | Glutamic acid and derivatives |
| SMILES | N[C@@H](CCC(O)=O)C(O)=O |
| Pathways | Histidinemia; Guanidinoacetate Methyltransferase Deficiency (GAMT Deficiency); 3-Methylglutaconic Aciduria Type I; beta-Ketothiolase Deficiency; Purine Nucleoside Phosphorylase Deficiency; Tyrosine Metabolism; Ketoprofen Action Pathway; Glutamate Metabolism; Argininosuccinic Aciduria; Salla Disease/Infantile Sialic Acid Storage Disease; Tyrosinemia Type I; Hyperinsulinism-Hyperammonemia Syndrome; 2-Methyl-3-hydroxybutryl-CoA Dehydrogenase Deficiency; Glutaric Aciduria Type I; Propanoate Metabolism; Celecoxib Action Pathway; Glycine and Serine Metabolism; Suprofen Action Pathway; Indomethacin Action Pathway; Carbamoyl Phosphate Synthetase Deficiency; Sialuria or French Type Sialuria; Ibuprofen Action Pathway; Saccharopinuria/Hyperlysinemia II; Histidine Metabolism; Arginine and Proline Metabolism; Purine Metabolism; Diflunisal Action Pathway; Etodolac Action Pathway; Ammonia Recycling |
| PharmGKB | PA449776 |
| ChEMBL | CHEMBL575060 |
