| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10009017 | HBV | ENSG00000106688.12 | protein_coding | SLC1A1 | No | No | 6505 | P43005 |
| TVIS10012063 | HBV | ENSG00000106688.12 | protein_coding | SLC1A1 | No | No | 6505 | P43005 |
| TVIS10012064 | HBV | ENSG00000106688.12 | protein_coding | SLC1A1 | No | No | 6505 | P43005 |
| TVIS10038252 | HBV | ENSG00000106688.12 | protein_coding | SLC1A1 | No | No | 6505 | P43005 |
| TVIS30074082 | HIV | ENSG00000106688.12 | protein_coding | SLC1A1 | No | No | 6505 | P43005 |
| TVIS30070672 | HIV | ENSG00000106688.12 | protein_coding | SLC1A1 | No | No | 6505 | P43005 |
| TVIS20033303 | HPV | ENSG00000106688.12 | protein_coding | SLC1A1 | No | No | 6505 | P43005 |
| TVIS44030674 | HTLV-1 | ENSG00000106688.12 | protein_coding | SLC1A1 | No | No | 6505 | P43005 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | SLC1A1 |
|---|---|
| DrugBank ID | DB00128 |
| Drug Name | Aspartic acid |
| Target ID | BE0001054 |
| UniProt ID | P43005 |
| Regulation Type | |
| PubMed IDs | 17389249; 17535962; 17346885; 17663137 |
| Citations | Tao Z, Grewer C: Cooperation of the conserved aspartate 439 and bound amino acid substrate is important for high-affinity Na+ binding to the glutamate transporter EAAC1. J Gen Physiol. 2007 Apr;129(4):331-44.@@Teichman S, Kanner BI: Aspartate-444 is essential for productive substrate interactions in a neuronal glutamate transporter. J Gen Physiol. 2007 Jun;129(6):527-39.@@Tai YH, Wang YH, Tsai RY, Wang JJ, Tao PL, Liu TM, Wang YC, Wong CS: Amitriptyline preserves morphine's antinociceptive effect by regulating the glutamate transporter GLAST and GLT-1 trafficking and excitatory amino acids concentration in morphine-tolerant rats. Pain. 2007 Jun;129(3):343-54. Epub 2007 Mar 7.@@Ozawa S: [Role of glutamate transporters in excitatory synapses in cerebellar Purkinje cells]. Brain Nerve. 2007 Jul;59(7):669-76. |
| Groups | Approved; Nutraceutical |
| Direct Classification | Aspartic acid and derivatives |
| SMILES | N[C@@H](CC(O)=O)C(O)=O |
| Pathways | Lesch-Nyhan Syndrome (LNS); Guanidinoacetate Methyltransferase Deficiency (GAMT Deficiency); Xanthinuria Type I; Hyperornithinemia with Gyrate Atrophy (HOGA); Purine Nucleoside Phosphorylase Deficiency; Carnosinuria, Carnosinemia; Tyrosine Metabolism; Disulfiram Action Pathway; Hyperprolinemia Type II; Glutamate Metabolism; Adenine Phosphoribosyltransferase Deficiency (APRT); Mercaptopurine Action Pathway; Argininosuccinic Aciduria; L-Arginine:Glycine Amidinotransferase Deficiency; Xanthine Dehydrogenase Deficiency (Xanthinuria); Tyrosinemia Type I; Hyperinsulinism-Hyperammonemia Syndrome; Arginine: Glycine Amidinotransferase Deficiency (AGAT Deficiency); Mitochondrial DNA Depletion Syndrome; Creatine Deficiency, Guanidinoacetate Methyltransferase Deficiency; Carbamoyl Phosphate Synthetase Deficiency; Hyperprolinemia Type I; Myoadenylate Deaminase Deficiency; Homocarnosinosis; Malate-Aspartate Shuttle; Arginine and Proline Metabolism; Purine Metabolism; Gout or Kelley-Seegmiller Syndrome; Adenylosuccinate Lyase Deficiency; Ammonia Recycling |
| PharmGKB | PA448494 |
| ChEMBL | CHEMBL274323 |
