| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10020992 | HBV | ENSG00000003989.18 | protein_coding | SLC7A2 | No | No | 6542 | P52569 |
| TVIS30068539 | HIV | ENSG00000003989.18 | protein_coding | SLC7A2 | No | No | 6542 | P52569 |
| TVIS20011203 | HPV | ENSG00000003989.18 | protein_coding | SLC7A2 | No | No | 6542 | P52569 |
| TVIS20046448 | HPV | ENSG00000003989.18 | protein_coding | SLC7A2 | No | No | 6542 | P52569 |
| TVIS20023625 | HPV | ENSG00000003989.18 | protein_coding | SLC7A2 | No | No | 6542 | P52569 |
| TVIS20066652 | HPV | ENSG00000003989.18 | protein_coding | SLC7A2 | No | No | 6542 | P52569 |
| TVIS44035611 | HTLV-1 | ENSG00000003989.18 | protein_coding | SLC7A2 | No | No | 6542 | P52569 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | SLC7A2 |
|---|---|
| DrugBank ID | DB00129 |
| Drug Name | Ornithine |
| Target ID | BE0000562 |
| UniProt ID | P52569 |
| Regulation Type | |
| PubMed IDs | 16703566; 17065601; 12679322 |
| Citations | Yeramian A, Martin L, Arpa L, Bertran J, Soler C, McLeod C, Modolell M, Palacin M, Lloberas J, Celada A: Macrophages require distinct arginine catabolism and transport systems for proliferation and for activation. Eur J Immunol. 2006 Jun;36(6):1516-26.@@Cerec V, Piquet-Pellorce C, Aly HA, Touzalin AM, Jegou B, Bauche F: Multiple pathways for cationic amino acid transport in rat seminiferous tubule cells. Biol Reprod. 2007 Feb;76(2):241-9. Epub 2006 Oct 25.@@Endo M, Oyadomari S, Terasaki Y, Takeya M, Suga M, Mori M, Gotoh T: Induction of arginase I and II in bleomycin-induced fibrosis of mouse lung. Am J Physiol Lung Cell Mol Physiol. 2003 Aug;285(2):L313-21. Epub 2003 Apr 4. |
| Groups | Approved; Nutraceutical |
| Direct Classification | L-alpha-amino acids |
| SMILES | NCCC[C@H](N)C(O)=O |
| Pathways | Citrullinemia Type I; Guanidinoacetate Methyltransferase Deficiency (GAMT Deficiency); Argininemia; Hyperornithinemia with Gyrate Atrophy (HOGA); Spermidine and Spermine Biosynthesis; Hyperprolinemia Type II; Argininosuccinic Aciduria; L-Arginine:Glycine Amidinotransferase Deficiency; Hyperornithinemia-Hyperammonemia-Homocitrullinuria [HHH-syndrome]; Arginine: Glycine Amidinotransferase Deficiency (AGAT Deficiency); Prolidase Deficiency (PD); Creatine Deficiency, Guanidinoacetate Methyltransferase Deficiency; Carbamoyl Phosphate Synthetase Deficiency; Ornithine Aminotransferase Deficiency (OAT Deficiency); Hyperprolinemia Type I; Arginine and Proline Metabolism; Ornithine Transcarbamylase Deficiency (OTC Deficiency); Prolinemia Type II; Urea Cycle |
| PharmGKB | PA164783814 |
| ChEMBL | CHEMBL446143 |
