| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10020992 | HBV | ENSG00000003989.18 | protein_coding | SLC7A2 | No | No | 6542 | P52569 |
| TVIS30068539 | HIV | ENSG00000003989.18 | protein_coding | SLC7A2 | No | No | 6542 | P52569 |
| TVIS20011203 | HPV | ENSG00000003989.18 | protein_coding | SLC7A2 | No | No | 6542 | P52569 |
| TVIS20046448 | HPV | ENSG00000003989.18 | protein_coding | SLC7A2 | No | No | 6542 | P52569 |
| TVIS20023625 | HPV | ENSG00000003989.18 | protein_coding | SLC7A2 | No | No | 6542 | P52569 |
| TVIS20066652 | HPV | ENSG00000003989.18 | protein_coding | SLC7A2 | No | No | 6542 | P52569 |
| TVIS44035611 | HTLV-1 | ENSG00000003989.18 | protein_coding | SLC7A2 | No | No | 6542 | P52569 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | SLC7A2 |
|---|---|
| DrugBank ID | DB00123 |
| Drug Name | Lysine |
| Target ID | BE0000562 |
| UniProt ID | P52569 |
| Regulation Type | |
| PubMed IDs | 17139284; 17016423; 7499219; 15746185; 12475743 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Low BC, Grigor MR: Angiotensin II stimulates system y+ and cationic amino acid transporter gene expression in cultured vascular smooth muscle cells. J Biol Chem. 1995 Nov 17;270(46):27577-83.@@Rotoli BM, Bussolati O, Sala R, Gazzola GC, Dall'Asta V: The transport of cationic amino acids in human airway cells: expression of system y+L activity and transepithelial delivery of NOS inhibitors. FASEB J. 2005 May;19(7):810-2. Epub 2005 Mar 3.@@Schwartz D, Schwartz IF, Gnessin E, Wollman Y, Chernichovsky T, Blum M, Iaina A: Differential regulation of glomerular arginine transporters (CAT-1 and CAT-2) in lipopolysaccharide-treated rats. Am J Physiol Renal Physiol. 2003 Apr;284(4):F788-95. Epub 2002 Dec 10. |
| Groups | Approved; Nutraceutical |
| Direct Classification | L-alpha-amino acids |
| SMILES | NCCCC[C@H](N)C(O)=O |
| Pathways | Multiple Carboxylase Deficiency, Neonatal or Early Onset Form; Biotin Metabolism; Glutaric Aciduria Type I; 2-Aminoadipic 2-Oxoadipic Aciduria; Hyperlysinemia II or Saccharopinuria; Hyperlysinemia I, Familial; Saccharopinuria/Hyperlysinemia II; Carnitine Synthesis; Lysine Degradation; Biotinidase Deficiency; Pyridoxine Dependency with Seizures |
| PharmGKB | PA450280 |
| ChEMBL | CHEMBL8085 |
