Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10012538HBVENSG00000057252.13protein_codingSOAT1NoNo6646P35610
TVIS10013403HBVENSG00000057252.13protein_codingSOAT1NoNo6646P35610
TVIS10012539HBVENSG00000057252.13protein_codingSOAT1NoNo6646P35610
TVIS30021119HIVENSG00000057252.13protein_codingSOAT1NoNo6646P35610
TVIS20048100HPVENSG00000057252.13protein_codingSOAT1NoNo6646P35610
TVIS44030650HTLV-1ENSG00000057252.13protein_codingSOAT1NoNo6646P35610
TVIS44037130HTLV-1ENSG00000057252.13protein_codingSOAT1NoNo6646P35610
TCGA Plot Options
Drug Information
GeneSOAT1
DrugBank IDDB01094
Drug NameHesperetin
Target IDBE0000105
UniProt IDP35610
Regulation Typeinhibitor
PubMed IDs11352979; 15114505
CitationsWilcox LJ, Borradaile NM, de Dreu LE, Huff MW: Secretion of hepatocyte apoB is inhibited by the flavonoids, naringenin and hesperetin, via reduced activity and expression of ACAT2 and MTP. J Lipid Res. 2001 May;42(5):725-34.@@Chung MY, Rho MC, Ko JS, Ryu SY, Jeune KH, Kim K, Lee HS, Kim YK: In vitro inhibition of diacylglycerol acyltransferase by prenylflavonoids from Sophora flavescens. Planta Med. 2004 Mar;70(3):258-60.
GroupsExperimental
Direct Classification4'-O-methylated flavonoids
SMILESCOC1=C(O)C=C(C=C1)[C@@H]1CC(=O)C2=C(O)C=C(O)C=C2O1
Pathways
PharmGKBPA164742902
ChEMBLCHEMBL399121