| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10012538 | HBV | ENSG00000057252.13 | protein_coding | SOAT1 | No | No | 6646 | P35610 |
| TVIS10013403 | HBV | ENSG00000057252.13 | protein_coding | SOAT1 | No | No | 6646 | P35610 |
| TVIS10012539 | HBV | ENSG00000057252.13 | protein_coding | SOAT1 | No | No | 6646 | P35610 |
| TVIS30021119 | HIV | ENSG00000057252.13 | protein_coding | SOAT1 | No | No | 6646 | P35610 |
| TVIS20048100 | HPV | ENSG00000057252.13 | protein_coding | SOAT1 | No | No | 6646 | P35610 |
| TVIS44030650 | HTLV-1 | ENSG00000057252.13 | protein_coding | SOAT1 | No | No | 6646 | P35610 |
| TVIS44037130 | HTLV-1 | ENSG00000057252.13 | protein_coding | SOAT1 | No | No | 6646 | P35610 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | SOAT1 |
|---|---|
| DrugBank ID | DB00973 |
| Drug Name | Ezetimibe |
| Target ID | BE0000105 |
| UniProt ID | P35610 |
| Regulation Type | inhibitor |
| PubMed IDs | 19669185; 20227438; 18442485 |
| Citations | Singh A, Basit A, Banerjee UC: Burkholderia cenocepacia: a new biocatalyst for efficient bioreduction of ezetimibe intermediate. J Ind Microbiol Biotechnol. 2009 Nov;36(11):1369-74. doi: 10.1007/s10295-009-0622-z. Epub 2009 Aug 8.@@Costet P: Molecular pathways and agents for lowering LDL-cholesterol in addition to statins. Pharmacol Ther. 2010 Jun;126(3):263-78. doi: 10.1016/j.pharmthera.2010.02.006. Epub 2010 Mar 19.@@Wang HH, Portincasa P, Mendez-Sanchez N, Uribe M, Wang DQ: Effect of ezetimibe on the prevention and dissolution of cholesterol gallstones. Gastroenterology. 2008 Jun;134(7):2101-10. doi: 10.1053/j.gastro.2008.03.011. Epub 2008 Mar 10. |
| Groups | Approved |
| Direct Classification | Monobactams |
| SMILES | [H][C@]1(CC[C@H](O)C2=CC=C(F)C=C2)C(=O)N(C2=CC=C(F)C=C2)[C@]1([H])C1=CC=C(O)C=C1 |
| Pathways | |
| PharmGKB | PA10816 |
| ChEMBL | CHEMBL1138 |
