Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10019173HBVENSG00000120907.18protein_codingADRA1ANoNo148B0ZBD3
P35348
TVIS10019323HBVENSG00000120907.18protein_codingADRA1ANoNo148B0ZBD3
P35348
TVIS10031044HBVENSG00000120907.18protein_codingADRA1ANoNo148B0ZBD3
P35348
TVIS10025139HBVENSG00000120907.18protein_codingADRA1ANoNo148B0ZBD3
P35348
TVIS10020261HBVENSG00000120907.18protein_codingADRA1ANoNo148B0ZBD3
P35348
TVIS10040464HBVENSG00000120907.18protein_codingADRA1ANoNo148B0ZBD3
P35348
TVIS20001928HPVENSG00000120907.18protein_codingADRA1ANoNo148B0ZBD3
P35348
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Drug Information
GeneADRA1A
DrugBank IDDB00458
Drug NameImipramine
Target IDBE0000501
UniProt IDP35348
Regulation Typeantagonist
PubMed IDs7855217; 20363235
CitationsCusack B, Nelson A, Richelson E: Binding of antidepressants to human brain receptors: focus on newer generation compounds. Psychopharmacology (Berl). 1994 May;114(4):559-65.@@Nojimoto FD, Mueller A, Hebeler-Barbosa F, Akinaga J, Lima V, Kiguti LR, Pupo AS: The tricyclic antidepressants amitriptyline, nortriptyline and imipramine are weak antagonists of human and rat alpha1B-adrenoceptors. Neuropharmacology. 2010 Jul-Aug;59(1-2):49-57. doi: 10.1016/j.neuropharm.2010.03.015. Epub 2010 Apr 2.
GroupsApproved
Direct ClassificationDibenzazepines
SMILESCN(C)CCCN1C2=CC=CC=C2CCC2=CC=CC=C12
PathwaysImipramine Metabolism Pathway; Imipramine Action Pathway
PharmGKBPA449969
ChEMBLCHEMBL11