| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10019173 | HBV | ENSG00000120907.18 | protein_coding | ADRA1A | No | No | 148 | B0ZBD3 P35348 |
| TVIS10019323 | HBV | ENSG00000120907.18 | protein_coding | ADRA1A | No | No | 148 | B0ZBD3 P35348 |
| TVIS10031044 | HBV | ENSG00000120907.18 | protein_coding | ADRA1A | No | No | 148 | B0ZBD3 P35348 |
| TVIS10025139 | HBV | ENSG00000120907.18 | protein_coding | ADRA1A | No | No | 148 | B0ZBD3 P35348 |
| TVIS10020261 | HBV | ENSG00000120907.18 | protein_coding | ADRA1A | No | No | 148 | B0ZBD3 P35348 |
| TVIS10040464 | HBV | ENSG00000120907.18 | protein_coding | ADRA1A | No | No | 148 | B0ZBD3 P35348 |
| TVIS20001928 | HPV | ENSG00000120907.18 | protein_coding | ADRA1A | No | No | 148 | B0ZBD3 P35348 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ADRA1A |
|---|---|
| DrugBank ID | DB00696 |
| Drug Name | Ergotamine |
| Target ID | BE0000501 |
| UniProt ID | P35348 |
| Regulation Type | partial agonist |
| PubMed IDs | 17139284; 17016423; 18066532 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Gornemann T, Jahnichen S, Schurad B, Latte KP, Horowski R, Tack J, Flieger M, Pertz HH: Pharmacological properties of a wide array of ergolines at functional alpha(1)-adrenoceptor subtypes. Naunyn Schmiedebergs Arch Pharmacol. 2008 Jan;376(5):321-30. Epub 2007 Dec 8. |
| Groups | Approved |
| Direct Classification | Ergotamines, dihydroergotamines, and derivatives |
| SMILES | [H][C@@]12CCCN1C(=O)[C@H](CC1=CC=CC=C1)N1C(=O)[C@](C)(NC(=O)[C@H]3CN(C)[C@]4([H])CC5=CNC6=CC=CC(=C56)C4=C3)O[C@@]21O |
| Pathways | |
| PharmGKB | PA164747651 |
| ChEMBL | CHEMBL442 |
