| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30059931 | HIV | ENSG00000151834.16 | protein_coding | GABRA2 | No | No | 2555 | E9PBQ7 P47869 |
| TVIS30059932 | HIV | ENSG00000151834.16 | protein_coding | GABRA2 | No | No | 2555 | E9PBQ7 P47869 |
| TVIS30059933 | HIV | ENSG00000151834.16 | protein_coding | GABRA2 | No | No | 2555 | E9PBQ7 P47869 |
| TVIS30059934 | HIV | ENSG00000151834.16 | protein_coding | GABRA2 | No | No | 2555 | E9PBQ7 P47869 |
| TVIS20058474 | HPV | ENSG00000151834.16 | protein_coding | GABRA2 | No | No | 2555 | E9PBQ7 P47869 |
| TVIS20037924 | HPV | ENSG00000151834.16 | protein_coding | GABRA2 | No | No | 2555 | E9PBQ7 P47869 |
| TVIS20067984 | HPV | ENSG00000151834.16 | protein_coding | GABRA2 | No | No | 2555 | E9PBQ7 P47869 |
| TVIS44019356 | HTLV-1 | ENSG00000151834.16 | protein_coding | GABRA2 | No | No | 2555 | E9PBQ7 P47869 |
| TVIS44006829 | HTLV-1 | ENSG00000151834.16 | protein_coding | GABRA2 | No | No | 2555 | E9PBQ7 P47869 |
| TVIS44028343 | HTLV-1 | ENSG00000151834.16 | protein_coding | GABRA2 | No | No | 2555 | E9PBQ7 P47869 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | GABRA2 |
|---|---|
| DrugBank ID | DB13994 |
| Drug Name | AZD-7325 |
| Target ID | BE0000381 |
| UniProt ID | P47869 |
| Regulation Type | positive allosteric modulator |
| PubMed IDs | 22122233; 24802722 |
| Citations | Zhou D, Sunzel M, Ribadeneira MD, Smith MA, Desai D, Lin J, Grimm SW: A clinical study to assess CYP1A2 and CYP3A4 induction by AZD7325, a selective GABA(A) receptor modulator - an in vitro and in vivo comparison. Br J Clin Pharmacol. 2012 Jul;74(1):98-108. doi: 10.1111/j.1365-2125.2011.04155.x.@@Chen X, Jacobs G, de Kam M, Jaeger J, Lappalainen J, Maruff P, Smith MA, Cross AJ, Cohen A, van Gerven J: The central nervous system effects of the partial GABA-Aalpha2,3 -selective receptor modulator AZD7325 in comparison with lorazepam in healthy males. Br J Clin Pharmacol. 2014 Dec;78(6):1298-314. doi: 10.1111/bcp.12413. |
| Groups | Investigational |
| Direct Classification | |
| SMILES | CCCNC(=O)C1=C(N)C2=CC=CC(=C2N=N1)C1=C(F)C=CC=C1OC |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL1783282 |
