Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS46000247BKPyvENSG00000113580.15protein_codingNR3C1NoNo2908E5KQF5
E5KQF6
F1D8N4
P04150
TVIS46000268BKPyvENSG00000113580.15protein_codingNR3C1NoNo2908E5KQF5
E5KQF6
F1D8N4
P04150
TVIS30003768HIVENSG00000113580.15protein_codingNR3C1NoNo2908E5KQF5
E5KQF6
F1D8N4
P04150
TVIS30013351HIVENSG00000113580.15protein_codingNR3C1NoNo2908E5KQF5
E5KQF6
F1D8N4
P04150
TVIS30008906HIVENSG00000113580.15protein_codingNR3C1NoNo2908E5KQF5
E5KQF6
F1D8N4
P04150
TVIS30003769HIVENSG00000113580.15protein_codingNR3C1NoNo2908E5KQF5
E5KQF6
F1D8N4
P04150
TVIS30016333HIVENSG00000113580.15protein_codingNR3C1NoNo2908E5KQF5
E5KQF6
F1D8N4
P04150
TVIS30016334HIVENSG00000113580.15protein_codingNR3C1NoNo2908E5KQF5
E5KQF6
F1D8N4
P04150
TVIS30008907HIVENSG00000113580.15protein_codingNR3C1NoNo2908E5KQF5
E5KQF6
F1D8N4
P04150
TVIS30000694HIVENSG00000113580.15protein_codingNR3C1NoNo2908E5KQF5
E5KQF6
F1D8N4
P04150
TCGA Plot Options
Drug Information
GeneNR3C1
DrugBank IDDB00838
Drug NameClocortolone
Target IDBE0000794
UniProt IDP04150
Regulation Typeagonist
PubMed IDs18691892; 18022656; 12188035
CitationsAli A, Balkovec JM, Greenlee M, Hammond ML, Rouen G, Taylor G, Einstein M, Ge L, Harris G, Kelly TM, Mazur P, Pandit S, Santoro J, Sitlani A, Wang C, Williamson J, Forrest MJ, Carballo-Jane E, Luell S, Lowitz K, Visco D: Discovery of betamethasone 17alpha-carbamates as dissociated glucocorticoid receptor modulators in the rat. Bioorg Med Chem. 2008 Aug 15;16(16):7535-42. doi: 10.1016/j.bmc.2008.07.037. Epub 2008 Jul 20.@@Buchwald P: Glucocorticoid receptor binding: a biphasic dependence on molecular size as revealed by the bilinear LinBiExp model. Steroids. 2008 Feb;73(2):193-208. Epub 2007 Oct 11.@@Tanigawa K, Nagase H, Ohmori K, Tanaka K, Miyake H, Kiniwa M, Ikizawa K: Species-specific differences in the glucocorticoid receptor transactivation function upon binding with betamethasone-esters. Int Immunopharmacol. 2002 Jun;2(7):941-50.
GroupsApproved
Direct Classification21-hydroxysteroids
SMILES[H][C@@]12C[C@@H](C)[C@H](C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1(Cl)[C@@]2([H])C[C@H](F)C2=CC(=O)C=C[C@]12C
Pathways
PharmGKBPA164744013
ChEMBL