Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS46000247BKPyvENSG00000113580.15protein_codingNR3C1NoNo2908E5KQF5
E5KQF6
F1D8N4
P04150
TVIS46000268BKPyvENSG00000113580.15protein_codingNR3C1NoNo2908E5KQF5
E5KQF6
F1D8N4
P04150
TVIS30003768HIVENSG00000113580.15protein_codingNR3C1NoNo2908E5KQF5
E5KQF6
F1D8N4
P04150
TVIS30013351HIVENSG00000113580.15protein_codingNR3C1NoNo2908E5KQF5
E5KQF6
F1D8N4
P04150
TVIS30008906HIVENSG00000113580.15protein_codingNR3C1NoNo2908E5KQF5
E5KQF6
F1D8N4
P04150
TVIS30003769HIVENSG00000113580.15protein_codingNR3C1NoNo2908E5KQF5
E5KQF6
F1D8N4
P04150
TVIS30016333HIVENSG00000113580.15protein_codingNR3C1NoNo2908E5KQF5
E5KQF6
F1D8N4
P04150
TVIS30016334HIVENSG00000113580.15protein_codingNR3C1NoNo2908E5KQF5
E5KQF6
F1D8N4
P04150
TVIS30008907HIVENSG00000113580.15protein_codingNR3C1NoNo2908E5KQF5
E5KQF6
F1D8N4
P04150
TVIS30000694HIVENSG00000113580.15protein_codingNR3C1NoNo2908E5KQF5
E5KQF6
F1D8N4
P04150
TCGA Plot Options
Drug Information
GeneNR3C1
DrugBank IDDB01260
Drug NameDesonide
Target IDBE0000794
UniProt IDP04150
Regulation Typeagonist
PubMed IDs20427668; 17038445; 20371666
CitationsRussell GM, Henley DE, Leendertz J, Douthwaite JA, Wood SA, Stevens A, Woltersdorf WW, Peeters BW, Ruigt GS, White A, Veldhuis JD, Lightman SL: Rapid glucocorticoid receptor-mediated inhibition of hypothalamic-pituitary-adrenal ultradian activity in healthy males. J Neurosci. 2010 Apr 28;30(17):6106-15. doi: 10.1523/JNEUROSCI.5332-09.2010.@@Shaw JR, Gabor K, Hand E, Lankowski A, Durant L, Thibodeau R, Stanton CR, Barnaby R, Coutermarsh B, Karlson KH, Sato JD, Hamilton JW, Stanton BA: Role of glucocorticoid receptor in acclimation of killifish (Fundulus heteroclitus) to seawater and effects of arsenic. Am J Physiol Regul Integr Comp Physiol. 2007 Feb;292(2):R1052-60. Epub 2006 Oct 12.@@Otte C, Wust S, Zhao S, Pawlikowska L, Kwok PY, Whooley MA: Glucocorticoid receptor gene, low-grade inflammation, and heart failure: the Heart and Soul study. J Clin Endocrinol Metab. 2010 Jun;95(6):2885-91. doi: 10.1210/jc.2009-2251. Epub 2010 Apr 6.
GroupsApproved; Investigational
Direct Classification21-hydroxysteroids
SMILES[H][C@@]12C[C@H]3OC(C)(C)O[C@@]3(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1([H])[C@@]2([H])CCC2=CC(=O)C=C[C@]12C
Pathways
PharmGKBPA164776996
ChEMBLCHEMBL1201109