Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS30076298HIVENSG00000113580.15protein_codingNR3C1NoNo2908E5KQF5
E5KQF6
F1D8N4
P04150
TVIS30018918HIVENSG00000113580.15protein_codingNR3C1NoNo2908E5KQF5
E5KQF6
F1D8N4
P04150
TVIS30063743HIVENSG00000113580.15protein_codingNR3C1NoNo2908E5KQF5
E5KQF6
F1D8N4
P04150
TVIS30063744HIVENSG00000113580.15protein_codingNR3C1NoNo2908E5KQF5
E5KQF6
F1D8N4
P04150
TVIS30063745HIVENSG00000113580.15protein_codingNR3C1NoNo2908E5KQF5
E5KQF6
F1D8N4
P04150
TVIS30063746HIVENSG00000113580.15protein_codingNR3C1NoNo2908E5KQF5
E5KQF6
F1D8N4
P04150
TVIS30063747HIVENSG00000113580.15protein_codingNR3C1NoNo2908E5KQF5
E5KQF6
F1D8N4
P04150
TVIS30063748HIVENSG00000113580.15protein_codingNR3C1NoNo2908E5KQF5
E5KQF6
F1D8N4
P04150
TVIS30063749HIVENSG00000113580.15protein_codingNR3C1NoNo2908E5KQF5
E5KQF6
F1D8N4
P04150
TVIS30063750HIVENSG00000113580.15protein_codingNR3C1NoNo2908E5KQF5
E5KQF6
F1D8N4
P04150
TCGA Plot Options
Drug Information
GeneNR3C1
DrugBank IDDB00838
Drug NameClocortolone
Target IDBE0000794
UniProt IDP04150
Regulation Typeagonist
PubMed IDs18691892; 18022656; 12188035
CitationsAli A, Balkovec JM, Greenlee M, Hammond ML, Rouen G, Taylor G, Einstein M, Ge L, Harris G, Kelly TM, Mazur P, Pandit S, Santoro J, Sitlani A, Wang C, Williamson J, Forrest MJ, Carballo-Jane E, Luell S, Lowitz K, Visco D: Discovery of betamethasone 17alpha-carbamates as dissociated glucocorticoid receptor modulators in the rat. Bioorg Med Chem. 2008 Aug 15;16(16):7535-42. doi: 10.1016/j.bmc.2008.07.037. Epub 2008 Jul 20.@@Buchwald P: Glucocorticoid receptor binding: a biphasic dependence on molecular size as revealed by the bilinear LinBiExp model. Steroids. 2008 Feb;73(2):193-208. Epub 2007 Oct 11.@@Tanigawa K, Nagase H, Ohmori K, Tanaka K, Miyake H, Kiniwa M, Ikizawa K: Species-specific differences in the glucocorticoid receptor transactivation function upon binding with betamethasone-esters. Int Immunopharmacol. 2002 Jun;2(7):941-50.
GroupsApproved
Direct Classification21-hydroxysteroids
SMILES[H][C@@]12C[C@@H](C)[C@H](C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1(Cl)[C@@]2([H])C[C@H](F)C2=CC(=O)C=C[C@]12C
Pathways
PharmGKBPA164744013
ChEMBL