| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10005352 | HBV | ENSG00000089250.20 | protein_coding | NOS1 | No | No | 4842 | A0PJJ7 B3VK56 P29475 |
| TVIS30077759 | HIV | ENSG00000089250.20 | protein_coding | NOS1 | No | No | 4842 | A0PJJ7 B3VK56 P29475 |
| TVIS30086944 | HIV | ENSG00000089250.20 | protein_coding | NOS1 | No | No | 4842 | A0PJJ7 B3VK56 P29475 |
| TVIS30085367 | HIV | ENSG00000089250.20 | protein_coding | NOS1 | No | No | 4842 | A0PJJ7 B3VK56 P29475 |
| TVIS30034193 | HIV | ENSG00000089250.20 | protein_coding | NOS1 | No | No | 4842 | A0PJJ7 B3VK56 P29475 |
| TVIS20050828 | HPV | ENSG00000089250.20 | protein_coding | NOS1 | No | No | 4842 | A0PJJ7 B3VK56 P29475 |
| TVIS20050514 | HPV | ENSG00000089250.20 | protein_coding | NOS1 | No | No | 4842 | A0PJJ7 B3VK56 P29475 |
| TVIS20025606 | HPV | ENSG00000089250.20 | protein_coding | NOS1 | No | No | 4842 | A0PJJ7 B3VK56 P29475 |
| TVIS20025607 | HPV | ENSG00000089250.20 | protein_coding | NOS1 | No | No | 4842 | A0PJJ7 B3VK56 P29475 |
| TVIS20031456 | HPV | ENSG00000089250.20 | protein_coding | NOS1 | No | No | 4842 | A0PJJ7 B3VK56 P29475 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | NOS1 |
|---|---|
| DrugBank ID | DB09241 |
| Drug Name | Methylene blue |
| Target ID | BE0000067 |
| UniProt ID | P29475 |
| Regulation Type | inhibitor |
| PubMed IDs | 7679577; 21547182; 10224309; 19760660 |
| Citations | Mayer B, Brunner F, Schmidt K: Inhibition of nitric oxide synthesis by methylene blue. Biochem Pharmacol. 1993 Jan 26;45(2):367-74. doi: 10.1016/0006-2952(93)90072-5.@@Ginimuge PR, Jyothi SD: Methylene blue: revisited. J Anaesthesiol Clin Pharmacol. 2010 Oct;26(4):517-20.@@Volke V, Wegener G, Vasar E, Rosenberg R: Methylene blue inhibits hippocampal nitric oxide synthase activity in vivo. Brain Res. 1999 May 1;826(2):303-5. doi: 10.1016/s0006-8993(99)01253-6.@@Oz M, Lorke DE, Hasan M, Petroianu GA: Cellular and molecular actions of Methylene Blue in the nervous system. Med Res Rev. 2011 Jan;31(1):93-117. doi: 10.1002/med.20177. |
| Groups | Approved; Investigational |
| Direct Classification | Benzothiazines |
| SMILES | [Cl-].CN(C)C1=CC2=[S+]C3=C(C=CC(=C3)N(C)C)N=C2C=C1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL405110 |
