| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10017926 | HBV | ENSG00000175899.15 | protein_coding | A2M | No | No | 2 | P01023 |
| TVIS10017460 | HBV | ENSG00000175899.15 | protein_coding | A2M | No | No | 2 | P01023 |
| TVIS10033096 | HBV | ENSG00000175899.15 | protein_coding | A2M | No | No | 2 | P01023 |
| TVIS10035096 | HBV | ENSG00000175899.15 | protein_coding | A2M | No | No | 2 | P01023 |
| TVIS10018412 | HBV | ENSG00000175899.15 | protein_coding | A2M | No | No | 2 | P01023 |
| TVIS10019448 | HBV | ENSG00000175899.15 | protein_coding | A2M | No | No | 2 | P01023 |
| TVIS10045150 | HBV | ENSG00000175899.15 | protein_coding | A2M | No | No | 2 | P01023 |
| TVIS30011672 | HIV | ENSG00000175899.15 | protein_coding | A2M | No | No | 2 | P01023 |
| TVIS30002004 | HIV | ENSG00000175899.15 | protein_coding | A2M | No | No | 2 | P01023 |
| TVIS30080257 | HIV | ENSG00000175899.15 | protein_coding | A2M | No | No | 2 | P01023 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | A2M |
|---|---|
| DrugBank ID | DB00626 |
| Drug Name | Bacitracin |
| Target ID | BE0000910 |
| UniProt ID | P01023 |
| Regulation Type | inhibitor |
| PubMed IDs | 42903; 6162847; 6165617; 6184373; 6187372 |
| Citations | Maxfield FR, Davies PJ, Klempner L, Willingham MC, Pastan I: Epidermal growth factor stimulation of DNA synthesis is potentiated by compounds that inhibit its clustering in coated pits. Proc Natl Acad Sci U S A. 1979 Nov;76(11):5731-5.@@Dickson RB, Willingham MC, Pastan I: Binding and internalization of 125I-alpha 2-macroglobulin by cultured fibroblasts. J Biol Chem. 1981 Apr 10;256(7):3454-9.@@Dickson RB, Willingham MC, Gallo M, Pastan I: Inhibition by bacitracin of high affinity binding of 125I-alpha 2M to plasma membranes. FEBS Lett. 1981 Apr 20;126(2):265-8.@@Hanover JA, Cheng S, Willingham MC, Pastan IH: alpha 2-Macroglobulin binding to cultured fibroblasts. Solubilization and partial purification of binding sites. J Biol Chem. 1983 Jan 10;258(1):370-7.@@Gliemann J, Larsen TR, Sottrup-Jensen L: Cell association and degradation of alpha 2-macroglobulin-trypsin complexes in hepatocytes and adipocytes. Biochim Biophys Acta. 1983 Mar 31;756(2):230-7. |
| Groups | Approved; Vet_approved |
| Direct Classification | Polypeptides |
| SMILES | CC[C@H](C)[C@H](N)C1=N[C@@H](CS1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@H]1CCCCNC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@H](CC2=CNC=N2)NC(=O)[C@@H](CC2=CC=CC=C2)NC(=O)[C@@H](NC(=O)[C@@H](CCCN)NC1=O)[C@@H](C)CC |
| Pathways | |
| PharmGKB | PA448531 |
| ChEMBL | CHEMBL1200558 |
