Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10006515HBVENSG00000023839.12protein_codingABCC2NoNo1244Q92887
TVIS10019341HBVENSG00000023839.12protein_codingABCC2NoNo1244Q92887
TCGA Plot Options
Drug Information
GeneABCC2
DrugBank IDDB16407
Drug NameAzvudine
Target IDBE0001069
UniProt IDQ92887
Regulation Typeregulator
PubMed IDs28487144
CitationsLiu Y, Liu B, Zhang Y, Peng Y, Huang C, Wang N, Jiang J, Wang Q, Chang J: Intestinal absorption mechanisms of 2'-deoxy-2'-beta-fluoro-4'-azidocytidine, a cytidine analog for AIDS treatment, and its interaction with P-glycoprotein, multidrug resistance-associated protein 2 and breast cancer resistance protein. Eur J Pharm Sci. 2017 Jul 15;105:150-158. doi: 10.1016/j.ejps.2017.05.009. Epub 2017 May 6.
GroupsInvestigational
Direct Classification
SMILESNC1=NC(=O)N(C=C1)[C@@H]1O[C@@](CO)(N=[N+]=[N-])[C@@H](O)[C@@H]1F
Pathways
PharmGKB
ChEMBLCHEMBL519846